EFFECT OF CORNUS FRUIT EXTRACTS ON OXIDATIVE STRESS IN DIABETES
The biological effects of fruits from different cultivars of the cornelian cherry under diabetes mellitus remain unclear. Aim. This study was purposed to investigate the effect of fruit extracts from various cultivars of Cornus mas L. on primary biomarkers of oxidative stress. Materials and Me...
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| Format: | Article |
| Language: | English |
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National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2025-04-01
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| Series: | Biotechnologia Acta |
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| Online Access: | https://biotechnology.kiev.ua/images/BTA/2025/2_2025/Moroz2_2025%20.pdf |
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| author | A.А. Moroz I.V. Brodyak A.Z. Kucharska N.O. Sybirna |
| author_facet | A.А. Moroz I.V. Brodyak A.Z. Kucharska N.O. Sybirna |
| author_sort | A.А. Moroz |
| collection | DOAJ |
| description | The biological effects of fruits from different cultivars of the cornelian cherry under diabetes mellitus remain unclear.
Aim. This study was purposed to investigate the effect of fruit extracts from various cultivars of Cornus mas L. on primary biomarkers of oxidative stress.
Materials and Methods: oxidative stress metabolites in erythrocytes were assessed by measuring the level of lipid peroxidation and protein oxidation products.
Results. The administration of C. mas and C. mas × C. officinalis hybrids fruit extracts to diabetic rats significantly reduced oxidative stress metabolite levels in erythrocytes.
Conclusions: сornelian cherry fruit extracts are perspective drugs that help inhibit oxidative stress development in erythrocytes under diabetic conditions. |
| format | Article |
| id | doaj-art-9289d85e52fa4d619f59b39ea071e20b |
| institution | DOAJ |
| issn | 2410-7751 2410-776X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry |
| record_format | Article |
| series | Biotechnologia Acta |
| spelling | doaj-art-9289d85e52fa4d619f59b39ea071e20b2025-08-20T03:23:31ZengNational Academy of Sciences of Ukraine, Palladin Institute of BiochemistryBiotechnologia Acta2410-77512410-776X2025-04-01182606210.15407/biotech18.02.060EFFECT OF CORNUS FRUIT EXTRACTS ON OXIDATIVE STRESS IN DIABETESA.А. Moroz0 I.V. Brodyak1 A.Z. Kucharska2N.O. Sybirna3Ivan Franko National University of Lviv, UkraineIvan Franko National University of Lviv, UkraineWrocław University of Environmental and Life Sciences, PolandIvan Franko National University of Lviv, UkraineThe biological effects of fruits from different cultivars of the cornelian cherry under diabetes mellitus remain unclear. Aim. This study was purposed to investigate the effect of fruit extracts from various cultivars of Cornus mas L. on primary biomarkers of oxidative stress. Materials and Methods: oxidative stress metabolites in erythrocytes were assessed by measuring the level of lipid peroxidation and protein oxidation products. Results. The administration of C. mas and C. mas × C. officinalis hybrids fruit extracts to diabetic rats significantly reduced oxidative stress metabolite levels in erythrocytes. Conclusions: сornelian cherry fruit extracts are perspective drugs that help inhibit oxidative stress development in erythrocytes under diabetic conditions. https://biotechnology.kiev.ua/images/BTA/2025/2_2025/Moroz2_2025%20.pdfсornelian cherrydiabetes mellituserythrocytesoxidative stressthiobarbituric acid reactive substancesadvanced oxidative protein productsoxidatively modified proteins. |
| spellingShingle | A.А. Moroz I.V. Brodyak A.Z. Kucharska N.O. Sybirna EFFECT OF CORNUS FRUIT EXTRACTS ON OXIDATIVE STRESS IN DIABETES Biotechnologia Acta сornelian cherry diabetes mellitus erythrocytes oxidative stress thiobarbituric acid reactive substances advanced oxidative protein products oxidatively modified proteins. |
| title | EFFECT OF CORNUS FRUIT EXTRACTS ON OXIDATIVE STRESS IN DIABETES |
| title_full | EFFECT OF CORNUS FRUIT EXTRACTS ON OXIDATIVE STRESS IN DIABETES |
| title_fullStr | EFFECT OF CORNUS FRUIT EXTRACTS ON OXIDATIVE STRESS IN DIABETES |
| title_full_unstemmed | EFFECT OF CORNUS FRUIT EXTRACTS ON OXIDATIVE STRESS IN DIABETES |
| title_short | EFFECT OF CORNUS FRUIT EXTRACTS ON OXIDATIVE STRESS IN DIABETES |
| title_sort | effect of cornus fruit extracts on oxidative stress in diabetes |
| topic | сornelian cherry diabetes mellitus erythrocytes oxidative stress thiobarbituric acid reactive substances advanced oxidative protein products oxidatively modified proteins. |
| url | https://biotechnology.kiev.ua/images/BTA/2025/2_2025/Moroz2_2025%20.pdf |
| work_keys_str_mv | AT aamoroz effectofcornusfruitextractsonoxidativestressindiabetes AT ivbrodyak effectofcornusfruitextractsonoxidativestressindiabetes AT azkucharska effectofcornusfruitextractsonoxidativestressindiabetes AT nosybirna effectofcornusfruitextractsonoxidativestressindiabetes |