Activity of 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propandyоl (chlonisol) versus lomustine in intracranial transplanted tumor model in mice

Activity of 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propandyоl (chlonisol) versus lomustine in intracranial transplanted tumor model in mice

Background. Alkylating drugs have been used in tumor chemo therapy for many decades, and the search for effective compounds continues.The aim of the study was to study the activity of the developed new compound – 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol (chlonisol) in comparison with lo...

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Bibliographic Details
Main Authors: Yu. G. Zmitrichenko, A. N. Stukov, V. А. Aleksandrov, G. V. Tochilnikov, I. G. Murazov, D. Н. Latipova, L. V. Filatova, T. Yu. Semiglazova
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2022-12-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
chlonisol
lomustine
intracranial tumor transplantation
ehrlich's carcinoma
sarcoma 180
Online Access:https://www.pharmacokinetica.ru/jour/article/view/329
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