Insights into IAV Replication and Lipid Metabolism in Suspension-Adapted MDCK-STAT1-KO Cells
Objectives: The industrial production of influenza vaccines is facing significant challenges, particularly in improving virus production efficiency. Despite advances in cell culture technologies, our understanding of the production characteristics of high-yield suspension cell lines remains limited,...
Saved in:
| Main Authors: | Qian Ye, Hong Yao, Zhiying Xiao, Liang Zhao, Wen-Song Tan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-01-01
|
| Series: | Vaccines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-393X/13/2/106 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
USP1 inhibits influenza A and B virus replication in MDCK cells by mediating RIG-I deubiquitination
by: Yuejiao Liao, et al.
Published: (2025-05-01) -
Stability of vaccine strains of seasonal live attenuated influenza vaccines when adapted to MDCK cell culture
by: Victoria A. Matyushenko, et al.
Published: (2025-07-01) -
Adaptation of H2N2 influenza viruses with different receptor specificity to MDCK cells: opportunities for the development of a cell-based vaccine against pandemic H2N2 influenza
by: Victoria A. Matyushenko, et al.
Published: (2025-03-01) -
Ergosterol Protects Canine MDCK Cells from Gentamicin-Induced Damage by Modulating Autophagy and Apoptosis
by: Zhipeng Qin, et al.
Published: (2025-06-01) -
SREBP2-dependent lipid droplet formation enhances viral replication and deteriorates lung injury in mice following IAV infection
by: Xinsen Li, et al.
Published: (2025-12-01)