Front-Loading Sputum Microscopy Services: An Opportunity to Optimise Smear-Based Case Detection of Tuberculosis in High Prevalence Countries

Setting. Ethiopia, Nepal, Nigeria, and Yemen. Objective. To reduce the time to complete sputum microscopy. Design. Cross-sectional surveys enrolling 923 patients with chronic cough in the 4 countries and using similar protocols. Spot-morning-spot sputum specimens were collected. An additional spu...

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Main Authors: Andy Ramsay, Mohammed Ahmed Yassin, Alexis Cambanis, Susumu Hirao, Ahmad Almotawa, Mohamed Gammo, Lovett Lawson, Izabel Arbide, Nasher Al-Aghbari, Najla Al-Sonboli, Jeevan Bahadur Sherchand, Punita Gauchan, Luis Eduardo Cuevas
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Journal of Tropical Medicine
Online Access:http://dx.doi.org/10.1155/2009/398767
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author Andy Ramsay
Mohammed Ahmed Yassin
Alexis Cambanis
Susumu Hirao
Ahmad Almotawa
Mohamed Gammo
Lovett Lawson
Izabel Arbide
Nasher Al-Aghbari
Najla Al-Sonboli
Jeevan Bahadur Sherchand
Punita Gauchan
Luis Eduardo Cuevas
author_facet Andy Ramsay
Mohammed Ahmed Yassin
Alexis Cambanis
Susumu Hirao
Ahmad Almotawa
Mohamed Gammo
Lovett Lawson
Izabel Arbide
Nasher Al-Aghbari
Najla Al-Sonboli
Jeevan Bahadur Sherchand
Punita Gauchan
Luis Eduardo Cuevas
author_sort Andy Ramsay
collection DOAJ
description Setting. Ethiopia, Nepal, Nigeria, and Yemen. Objective. To reduce the time to complete sputum microscopy. Design. Cross-sectional surveys enrolling 923 patients with chronic cough in the 4 countries and using similar protocols. Spot-morning-spot sputum specimens were collected. An additional sputum specimen (Xspot) was collected one hour after the first, and the yields of the first two or the three specimens collected as spot-morning-spot or spot-Xspot-morning were compared. Results. 216 patients had ≥ one positive smear. 210 (97%) were identified by the spot-morning-spot, and 210 (97%) were identified by the spot-Xspot-morning specimens, with 203 and 200 identified by the first 2 specimens of each approach, respectively. Neither difference was significant. Conclusions. The time to complete smear microscopy could be reduced.
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spelling doaj-art-926ae0d797d14653b7a95f8ea60b43872025-08-20T02:09:55ZengWileyJournal of Tropical Medicine1687-96861687-96942009-01-01200910.1155/2009/398767398767Front-Loading Sputum Microscopy Services: An Opportunity to Optimise Smear-Based Case Detection of Tuberculosis in High Prevalence CountriesAndy Ramsay0Mohammed Ahmed Yassin1Alexis Cambanis2Susumu Hirao3Ahmad Almotawa4Mohamed Gammo5Lovett Lawson6Izabel Arbide7Nasher Al-Aghbari8Najla Al-Sonboli9Jeevan Bahadur Sherchand10Punita Gauchan11Luis Eduardo Cuevas12Liverpool School of Tropical Medicine, Liverpool L3 5QA, UKLiverpool School of Tropical Medicine, Liverpool L3 5QA, UKLiverpool School of Tropical Medicine, Liverpool L3 5QA, UKLiverpool School of Tropical Medicine, Liverpool L3 5QA, UKLiverpool School of Tropical Medicine, Liverpool L3 5QA, UKLiverpool School of Tropical Medicine, Liverpool L3 5QA, UKZankli Medical Centre, P.O. Box 7745, Abuja, NigeriaBushullo Major Health Centre, P.O. Box 5, Awassa, EthiopiaNational Tuberculosis Institute, Sana'a, YemenNational Tuberculosis Institute, Sana'a, YemenMicrobiology and Parasitology and Health Research Laboratory, Infectious and Tropical Disease Research Centre, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal P.O. Box 10404, NepalMicrobiology and Parasitology and Health Research Laboratory, Infectious and Tropical Disease Research Centre, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal P.O. Box 10404, NepalLiverpool School of Tropical Medicine, Liverpool L3 5QA, UKSetting. Ethiopia, Nepal, Nigeria, and Yemen. Objective. To reduce the time to complete sputum microscopy. Design. Cross-sectional surveys enrolling 923 patients with chronic cough in the 4 countries and using similar protocols. Spot-morning-spot sputum specimens were collected. An additional sputum specimen (Xspot) was collected one hour after the first, and the yields of the first two or the three specimens collected as spot-morning-spot or spot-Xspot-morning were compared. Results. 216 patients had ≥ one positive smear. 210 (97%) were identified by the spot-morning-spot, and 210 (97%) were identified by the spot-Xspot-morning specimens, with 203 and 200 identified by the first 2 specimens of each approach, respectively. Neither difference was significant. Conclusions. The time to complete smear microscopy could be reduced.http://dx.doi.org/10.1155/2009/398767
spellingShingle Andy Ramsay
Mohammed Ahmed Yassin
Alexis Cambanis
Susumu Hirao
Ahmad Almotawa
Mohamed Gammo
Lovett Lawson
Izabel Arbide
Nasher Al-Aghbari
Najla Al-Sonboli
Jeevan Bahadur Sherchand
Punita Gauchan
Luis Eduardo Cuevas
Front-Loading Sputum Microscopy Services: An Opportunity to Optimise Smear-Based Case Detection of Tuberculosis in High Prevalence Countries
Journal of Tropical Medicine
title Front-Loading Sputum Microscopy Services: An Opportunity to Optimise Smear-Based Case Detection of Tuberculosis in High Prevalence Countries
title_full Front-Loading Sputum Microscopy Services: An Opportunity to Optimise Smear-Based Case Detection of Tuberculosis in High Prevalence Countries
title_fullStr Front-Loading Sputum Microscopy Services: An Opportunity to Optimise Smear-Based Case Detection of Tuberculosis in High Prevalence Countries
title_full_unstemmed Front-Loading Sputum Microscopy Services: An Opportunity to Optimise Smear-Based Case Detection of Tuberculosis in High Prevalence Countries
title_short Front-Loading Sputum Microscopy Services: An Opportunity to Optimise Smear-Based Case Detection of Tuberculosis in High Prevalence Countries
title_sort front loading sputum microscopy services an opportunity to optimise smear based case detection of tuberculosis in high prevalence countries
url http://dx.doi.org/10.1155/2009/398767
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