DNA methylation in monozygotic twins discordant for acute lymphoblastic leukemia: a case report and systematic review

DNA methylation in monozygotic twins discordant for acute lymphoblastic leukemia: a case report and systematic review

Abstract Acute lymphoblastic leukemia (ALL) is a prevalent malignant hematologic disease characterized by the abnormal proliferation and accumulation of immature lymphocytes in bone marrow and lymphoid tissues. In our study, Oxford Nanopore Technologies (ONT) sequencing was performed to investigate...

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Bibliographic Details
Main Authors: Mao-ling Sun, Yang Li, Rong-xi Man, Si-wen Wang, Rong Guo, Ying Yang, Yu-qing Pan
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Clinical Epigenetics
Subjects:
Acute lymphoblastic leukemia
DNA methylation
Monozygotic twin
Systematic review
Online Access:https://doi.org/10.1186/s13148-025-01906-z
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