High-fat diet-induced osteoporosis in mice under hypoxic conditions

High-fat diet-induced osteoporosis in mice under hypoxic conditions

Abstract In the context of global aging, osteoporosis has emerged as a significant public health concern, with a relatively high prevalence observed in plateau regions. This study aimed to investigate the effects and underlying mechanisms of high-fat diet (HFD) and hypoxic conditions on bone metabol...

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Bibliographic Details
Main Authors: Yajun Qiao, Huimin Zheng, Ruiying Cheng, Juan Guo, Li Ji, Zhibin Liu, Lixin Wei, Hongtao Bi, Zhongshu Shan
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Musculoskeletal Disorders
Subjects:
Hypoxia
HFD
Bone metabolism
Gut
Online Access:https://doi.org/10.1186/s12891-025-08725-6
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