Triple-x syndrome accompanied by congenital adrenal hyperplasia: case report

The 47,XXX karyotype is a rare sex chromosome anomaly. This karyotype is usually not associated with a characteristic physical phenotype. In the presented case, a triple-X girl patient associated with 11beta-hydroxylase deficiency is identified. The case was referred to the Endocrinology Unit...

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Main Authors: Selim Kurtoğlu, M Emre Atabek, Mustafa Akçakuş, Yusuf Ozkul, Cetin Saatçi
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2004-10-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/2840
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author Selim Kurtoğlu
M Emre Atabek
Mustafa Akçakuş
Yusuf Ozkul
Cetin Saatçi
author_facet Selim Kurtoğlu
M Emre Atabek
Mustafa Akçakuş
Yusuf Ozkul
Cetin Saatçi
author_sort Selim Kurtoğlu
collection DOAJ
description The 47,XXX karyotype is a rare sex chromosome anomaly. This karyotype is usually not associated with a characteristic physical phenotype. In the presented case, a triple-X girl patient associated with 11beta-hydroxylase deficiency is identified. The case was referred to the Endocrinology Unit at six days of age because of ambiguous genitalia. The karyotype in this case was 47,XXX, an unexpected finding. Diagnosis of 47,XXX individuals remains difficult because specific clinical criteria used to identify this condition are not available. Congenital adrenal hyperplasia has not been previously reported in patients with triple-X syndrome.
format Article
id doaj-art-9252f426ebf949e6a3bfa3637883a936
institution OA Journals
issn 0041-4301
2791-6421
language English
publishDate 2004-10-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-9252f426ebf949e6a3bfa3637883a9362025-08-20T02:01:57ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212004-10-01464Triple-x syndrome accompanied by congenital adrenal hyperplasia: case reportSelim Kurtoğlu0M Emre AtabekMustafa AkçakuşYusuf OzkulCetin SaatçiDepartment of Pediatrics, Erciyes University Faculty of Medicine, Kayseri, Turkey. The 47,XXX karyotype is a rare sex chromosome anomaly. This karyotype is usually not associated with a characteristic physical phenotype. In the presented case, a triple-X girl patient associated with 11beta-hydroxylase deficiency is identified. The case was referred to the Endocrinology Unit at six days of age because of ambiguous genitalia. The karyotype in this case was 47,XXX, an unexpected finding. Diagnosis of 47,XXX individuals remains difficult because specific clinical criteria used to identify this condition are not available. Congenital adrenal hyperplasia has not been previously reported in patients with triple-X syndrome. https://turkjpediatr.org/article/view/2840
spellingShingle Selim Kurtoğlu
M Emre Atabek
Mustafa Akçakuş
Yusuf Ozkul
Cetin Saatçi
Triple-x syndrome accompanied by congenital adrenal hyperplasia: case report
The Turkish Journal of Pediatrics
title Triple-x syndrome accompanied by congenital adrenal hyperplasia: case report
title_full Triple-x syndrome accompanied by congenital adrenal hyperplasia: case report
title_fullStr Triple-x syndrome accompanied by congenital adrenal hyperplasia: case report
title_full_unstemmed Triple-x syndrome accompanied by congenital adrenal hyperplasia: case report
title_short Triple-x syndrome accompanied by congenital adrenal hyperplasia: case report
title_sort triple x syndrome accompanied by congenital adrenal hyperplasia case report
url https://turkjpediatr.org/article/view/2840
work_keys_str_mv AT selimkurtoglu triplexsyndromeaccompaniedbycongenitaladrenalhyperplasiacasereport
AT memreatabek triplexsyndromeaccompaniedbycongenitaladrenalhyperplasiacasereport
AT mustafaakcakus triplexsyndromeaccompaniedbycongenitaladrenalhyperplasiacasereport
AT yusufozkul triplexsyndromeaccompaniedbycongenitaladrenalhyperplasiacasereport
AT cetinsaatci triplexsyndromeaccompaniedbycongenitaladrenalhyperplasiacasereport