A Neural-Network-Based Approach to White Blood Cell Classification

This paper presents a new white blood cell classification system for the recognition of five types of white blood cells. We propose a new segmentation algorithm for the segmentation of white blood cells from smear images. The core idea of the proposed segmentation algorithm is to find a discriminati...

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Main Authors: Mu-Chun Su, Chun-Yen Cheng, Pa-Chun Wang
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/796371
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author Mu-Chun Su
Chun-Yen Cheng
Pa-Chun Wang
author_facet Mu-Chun Su
Chun-Yen Cheng
Pa-Chun Wang
author_sort Mu-Chun Su
collection DOAJ
description This paper presents a new white blood cell classification system for the recognition of five types of white blood cells. We propose a new segmentation algorithm for the segmentation of white blood cells from smear images. The core idea of the proposed segmentation algorithm is to find a discriminating region of white blood cells on the HSI color space. Pixels with color lying in the discriminating region described by an ellipsoidal region will be regarded as the nucleus and granule of cytoplasm of a white blood cell. Then, through a further morphological process, we can segment a white blood cell from a smear image. Three kinds of features (i.e., geometrical features, color features, and LDP-based texture features) are extracted from the segmented cell. These features are fed into three different kinds of neural networks to recognize the types of the white blood cells. To test the effectiveness of the proposed white blood cell classification system, a total of 450 white blood cells images were used. The highest overall correct recognition rate could reach 99.11% correct. Simulation results showed that the proposed white blood cell classification system was very competitive to some existing systems.
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publishDate 2014-01-01
publisher Wiley
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spelling doaj-art-9245796f2b07429ebef26de360de97182025-08-20T03:20:36ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/796371796371A Neural-Network-Based Approach to White Blood Cell ClassificationMu-Chun Su0Chun-Yen Cheng1Pa-Chun Wang2Department of Computer Science & Information Engineering, National Central University, Jhongli 32001, TaiwanDepartment of Computer Science & Information Engineering, National Central University, Jhongli 32001, TaiwanGeneral Hospital, Taipei 10656, TaiwanThis paper presents a new white blood cell classification system for the recognition of five types of white blood cells. We propose a new segmentation algorithm for the segmentation of white blood cells from smear images. The core idea of the proposed segmentation algorithm is to find a discriminating region of white blood cells on the HSI color space. Pixels with color lying in the discriminating region described by an ellipsoidal region will be regarded as the nucleus and granule of cytoplasm of a white blood cell. Then, through a further morphological process, we can segment a white blood cell from a smear image. Three kinds of features (i.e., geometrical features, color features, and LDP-based texture features) are extracted from the segmented cell. These features are fed into three different kinds of neural networks to recognize the types of the white blood cells. To test the effectiveness of the proposed white blood cell classification system, a total of 450 white blood cells images were used. The highest overall correct recognition rate could reach 99.11% correct. Simulation results showed that the proposed white blood cell classification system was very competitive to some existing systems.http://dx.doi.org/10.1155/2014/796371
spellingShingle Mu-Chun Su
Chun-Yen Cheng
Pa-Chun Wang
A Neural-Network-Based Approach to White Blood Cell Classification
The Scientific World Journal
title A Neural-Network-Based Approach to White Blood Cell Classification
title_full A Neural-Network-Based Approach to White Blood Cell Classification
title_fullStr A Neural-Network-Based Approach to White Blood Cell Classification
title_full_unstemmed A Neural-Network-Based Approach to White Blood Cell Classification
title_short A Neural-Network-Based Approach to White Blood Cell Classification
title_sort neural network based approach to white blood cell classification
url http://dx.doi.org/10.1155/2014/796371
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