The Relationship Between Intolerance of Uncertainty and Treatment Adherence: The Moderating Effect of Self-Compassion on the Chain Mediation Model
Xinping Shi,1 Yuexia Wang,1 Qisen Jia,2 Shengwei Peng,1,* Xing Liu,1,* Yongju Pei1 1Department of Respiratory and Critical Care Medicine, Henan Provincial People’s Hospital, Zhengzhou, Henan, People’s Republic of China; 2Department of Nursing, Henan Provincial People’s Hospital, Zhen...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2025-03-01
|
| Series: | Patient Preference and Adherence |
| Subjects: | |
| Online Access: | https://www.dovepress.com/the-relationship-between-intolerance-of-uncertainty-and-treatment-adhe-peer-reviewed-fulltext-article-PPA |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Xinping Shi,1 Yuexia Wang,1 Qisen Jia,2 Shengwei Peng,1,* Xing Liu,1,* Yongju Pei1 1Department of Respiratory and Critical Care Medicine, Henan Provincial People’s Hospital, Zhengzhou, Henan, People’s Republic of China; 2Department of Nursing, Henan Provincial People’s Hospital, Zhengzhou, Henan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yongju Pei, Department of Respiratory and Critical Care Medicine, Henan Provincial People’s Hospital, Zhengzhou, Henan, People’s Republic of China, Email de738822@163.comPurpose: The low follow-up compliance of young and middle-aged patients with newly diagnosed pulmonary nodules warrants attention, primarily due to a series of factors such as occupational, familial, and social pressures. Enhancing follow-up adherence is essential for preventing pulmonary nodule progression and reducing lung cancer mortality. Existing research indicates that intolerance of uncertainty is closely associated with patients’ follow-up compliance; however, further in-depth investigation into its influencing mechanisms and potential improvement strategies is required.Patients and Methods: This study conducted a questionnaire survey among 319 young and middle-aged patients newly diagnosed with pulmonary nodules, examining the moderating effect of self-compassion on follow-up compliance and investigating the chain intermediary role of negative interpretation bias and trust in linking intolerance of uncertainty to follow-up compliance.Results: The study found that women, urban residents, and patients over 50 years old demonstrated relatively higher follow-up compliance. Intolerance of uncertainty was found to negatively predict follow-up compliance and indirectly influenced patients’ follow-up behavior through the mediating effects of negative interpretation bias and trust. Furthermore, self-compassion significantly moderated the relationship between trust and follow-up compliance.Conclusion: The findings provide a solid theoretical foundation for developing multidimensional interventions targeting both protective and risk factors. Specifically, mitigating the impact of intolerance of uncertainty on follow-up compliance can improve long-term patient health outcomes. The novel application of the chain mediation model provides valuable insights for future research and clinical practice, particularly in enhancing patient engagement and adherence to follow-up care. Future longitudinal studies are needed to explore additional influencing factors and validate these findings.Keywords: IU, interpretation bias, trust, self-compassion, initial diagnosis of pulmonary nodules, compliance |
|---|---|
| ISSN: | 1177-889X |