Recurrent desmoid tumors with ureteric fistula: a case report and literature review

BackgroundDesmoid tumors (DT) is a rare soft tissue tumor classified as a borderline neoplasm. It exhibits locally aggressive growth and is prone to postoperative recurrence.Case presentationWe reported the first case of adolescent pelvic DT ureteral fistula, and report the patient's all progre...

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Main Authors: LongDi Yu, Chi Yuan, Kai Wang, JiaJie Li, Xue Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1573732/full
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author LongDi Yu
Chi Yuan
Kai Wang
JiaJie Li
Xue Ma
author_facet LongDi Yu
Chi Yuan
Kai Wang
JiaJie Li
Xue Ma
author_sort LongDi Yu
collection DOAJ
description BackgroundDesmoid tumors (DT) is a rare soft tissue tumor classified as a borderline neoplasm. It exhibits locally aggressive growth and is prone to postoperative recurrence.Case presentationWe reported the first case of adolescent pelvic DT ureteral fistula, and report the patient's all progress of diagnosis and treatment. A recurrent pelvic DT in an adolescent female patient who initially underwent surgical resection but experienced recurrence, was effectively treated with sorafenib. Later, however, the patient's tumor changed from solid to cystic solid mixed, increasing in size, and the patient developed right hydronephrosis and hydroureter. Patients who underwent right sided antegrade pyelography were diagnosed with right sided ureteral desmoid tumor fistula and urinary fistula-related pseudocysts. Following treatment with right sided percutaneous nephrostomy, their condition improved, with resolution of right sided hydronephrosis and hydroureter, as well as partial shrinkage of the cystic component.ConclusionDT can rarely result in the development of DT-ureteral fistulas. For patients with DT responsive to medical therapy, physicians should closely monitor tumor progression and pay attention to its invasion of adjacent organs and potential complications. Physicians need to balance therapeutic efficacy and quality of life when making treatment strategies for young patients.
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spelling doaj-art-92409787c93e4dfea70eb07d99e486602025-08-20T02:29:30ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-04-011310.3389/fped.2025.15737321573732Recurrent desmoid tumors with ureteric fistula: a case report and literature reviewLongDi YuChi YuanKai WangJiaJie LiXue MaBackgroundDesmoid tumors (DT) is a rare soft tissue tumor classified as a borderline neoplasm. It exhibits locally aggressive growth and is prone to postoperative recurrence.Case presentationWe reported the first case of adolescent pelvic DT ureteral fistula, and report the patient's all progress of diagnosis and treatment. A recurrent pelvic DT in an adolescent female patient who initially underwent surgical resection but experienced recurrence, was effectively treated with sorafenib. Later, however, the patient's tumor changed from solid to cystic solid mixed, increasing in size, and the patient developed right hydronephrosis and hydroureter. Patients who underwent right sided antegrade pyelography were diagnosed with right sided ureteral desmoid tumor fistula and urinary fistula-related pseudocysts. Following treatment with right sided percutaneous nephrostomy, their condition improved, with resolution of right sided hydronephrosis and hydroureter, as well as partial shrinkage of the cystic component.ConclusionDT can rarely result in the development of DT-ureteral fistulas. For patients with DT responsive to medical therapy, physicians should closely monitor tumor progression and pay attention to its invasion of adjacent organs and potential complications. Physicians need to balance therapeutic efficacy and quality of life when making treatment strategies for young patients.https://www.frontiersin.org/articles/10.3389/fped.2025.1573732/fulldesmoid tumorsadolescenceureteric fistulapercutaneous nephrostomycase report
spellingShingle LongDi Yu
Chi Yuan
Kai Wang
JiaJie Li
Xue Ma
Recurrent desmoid tumors with ureteric fistula: a case report and literature review
Frontiers in Pediatrics
desmoid tumors
adolescence
ureteric fistula
percutaneous nephrostomy
case report
title Recurrent desmoid tumors with ureteric fistula: a case report and literature review
title_full Recurrent desmoid tumors with ureteric fistula: a case report and literature review
title_fullStr Recurrent desmoid tumors with ureteric fistula: a case report and literature review
title_full_unstemmed Recurrent desmoid tumors with ureteric fistula: a case report and literature review
title_short Recurrent desmoid tumors with ureteric fistula: a case report and literature review
title_sort recurrent desmoid tumors with ureteric fistula a case report and literature review
topic desmoid tumors
adolescence
ureteric fistula
percutaneous nephrostomy
case report
url https://www.frontiersin.org/articles/10.3389/fped.2025.1573732/full
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AT chiyuan recurrentdesmoidtumorswithuretericfistulaacasereportandliteraturereview
AT kaiwang recurrentdesmoidtumorswithuretericfistulaacasereportandliteraturereview
AT jiajieli recurrentdesmoidtumorswithuretericfistulaacasereportandliteraturereview
AT xuema recurrentdesmoidtumorswithuretericfistulaacasereportandliteraturereview