Beyond mitotic arrest: the diverse effects of microtubule-targeting drugs on tumor vasculature

For decades microtubule-targeting agents (MTAs) have been a cornerstone of cancer treatment regimens and continue to be heavily employed as backbone chemotherapy in combination with new targeted agents. These drugs include both microtubule stabilizers (e.g. taxanes, ixabepilone) as well as destabili...

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Bibliographic Details
Main Author: April L Risinger
Format: Article
Language:English
Published: Springer Nature 2025-03-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.1038/s44321-025-00223-5
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