Synephrine Analogues as Glucocorticoid Receptor Agonists
This work carried out the synthesis of several new synephrine analogues by universal method. Some of the synthesized compounds showed cytotoxicity on myeloid leukaemia cells K562 and lymphoma cell line Granta-519. Molecular docking using the glucocorticoid receptor (GR) model (PDB identifier 1P93) w...
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| Main Authors: | Eugenia Oleynik, Ekaterina Mikhina, Diana Grigoreva, Varvara Maksimova, Lyubov Grebenkina, Andrey Valerevich Matveev, Ekaterina Zhidkova, Ekaterina Lesovaya, Marianna Yakubovskaya |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
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| Series: | Chemistry Proceedings |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-4583/14/1/58 |
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