Differential Expression Analyses on Human Aortic Tissue Reveal Novel Genes and Pathways Associated With Abdominal Aortic Aneurysm Onset and Progression

Differential Expression Analyses on Human Aortic Tissue Reveal Novel Genes and Pathways Associated With Abdominal Aortic Aneurysm Onset and Progression

Background Abdominal aortic aneurysms (AAAs) are focal dilatations of the abdominal aorta that expand progressively, increasing their risk of rupture. Rupture of an AAA is associated with high mortality rates, but the mechanisms underlying the initiation, expansion, and rupture of AAAs are not yet f...

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Main Authors: Gerard Temprano‐Sagrera, Olga Peypoch, Begoña Soto, Jaume Dilmé, Laura Calsina Juscafresa, David Davtian, Mireia de la Rosa Estadella, Lluís Nieto, Andrew Brown, José Román Escudero, Ana Viñuela, Mercedes Camacho, Maria Sabater‐Lleal
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
abdominal aortic aneurysm
allele‐specific expression
alternative splicing
differential expression
transcriptomics
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.036082
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