Drugs from poisonous plants: Ethnopharmacological relevance to modern perspectives

The world of plant diversity is endlessly fascinating and essential for life on Earth. Since the inception of early civilization, humans have utilized plants for several purposes, particularly for their medicinal value. While some plants are known for their toxicity, they also contain beneficial phy...

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Main Authors: Bhagya Lakhmi Rajbongshi, Ashis K. Mukherjee
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Toxicon: X
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590171025000025
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author Bhagya Lakhmi Rajbongshi
Ashis K. Mukherjee
author_facet Bhagya Lakhmi Rajbongshi
Ashis K. Mukherjee
author_sort Bhagya Lakhmi Rajbongshi
collection DOAJ
description The world of plant diversity is endlessly fascinating and essential for life on Earth. Since the inception of early civilization, humans have utilized plants for several purposes, particularly for their medicinal value. While some plants are known for their toxicity, they also contain beneficial phytochemicals that are important for both plants and humans, indicating their dual nature. This study aims to explore and synthesize the existing knowledge on various poisonous plant species found worldwide. It primarily focuses on the therapeutic potential of specific types of phytochemicals responsible for treating multiple diseases. This review includes a list of 70 poisonous plants with medicinal properties for treating various ailments, as well as some of their traditional uses. A few of these plants are emphasized, which have been tremendously explored and studied, hold significant potential to contribute to modern drug discovery. Furthermore, it addresses the possible prospects and challenges of using poisonous plants and their phytochemicals as therapeutic agents. Although the therapeutic potential of poisonous plants is substantial, many toxins remain unexplored. This review accentuates the need for rigorous scientific investigations, prior to clinical trials to validate their traditional uses, which would reveal the pharmacological interventions that will eventually advance human health and well-being.
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institution Kabale University
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series Toxicon: X
spelling doaj-art-92316edc73a64270868fc90ed78c1d702025-02-05T04:32:38ZengElsevierToxicon: X2590-17102025-03-0125100215Drugs from poisonous plants: Ethnopharmacological relevance to modern perspectivesBhagya Lakhmi Rajbongshi0Ashis K. Mukherjee1Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Paschim Boragaon, Garchuk, Guwahati, Assam, 781035, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, IndiaDivision of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Paschim Boragaon, Garchuk, Guwahati, Assam, 781035, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India; Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur, Assam, 784028, India; Corresponding author. Institute of Advanced Study in Science and Technology, Vigyan Path, Paschim Boragaon, Garchuk, Guwahati, Assam, 781035, India.The world of plant diversity is endlessly fascinating and essential for life on Earth. Since the inception of early civilization, humans have utilized plants for several purposes, particularly for their medicinal value. While some plants are known for their toxicity, they also contain beneficial phytochemicals that are important for both plants and humans, indicating their dual nature. This study aims to explore and synthesize the existing knowledge on various poisonous plant species found worldwide. It primarily focuses on the therapeutic potential of specific types of phytochemicals responsible for treating multiple diseases. This review includes a list of 70 poisonous plants with medicinal properties for treating various ailments, as well as some of their traditional uses. A few of these plants are emphasized, which have been tremendously explored and studied, hold significant potential to contribute to modern drug discovery. Furthermore, it addresses the possible prospects and challenges of using poisonous plants and their phytochemicals as therapeutic agents. Although the therapeutic potential of poisonous plants is substantial, many toxins remain unexplored. This review accentuates the need for rigorous scientific investigations, prior to clinical trials to validate their traditional uses, which would reveal the pharmacological interventions that will eventually advance human health and well-being.http://www.sciencedirect.com/science/article/pii/S2590171025000025Poisonous plantsTherapeutic agentsPhytochemicalsTraditional medicine
spellingShingle Bhagya Lakhmi Rajbongshi
Ashis K. Mukherjee
Drugs from poisonous plants: Ethnopharmacological relevance to modern perspectives
Toxicon: X
Poisonous plants
Therapeutic agents
Phytochemicals
Traditional medicine
title Drugs from poisonous plants: Ethnopharmacological relevance to modern perspectives
title_full Drugs from poisonous plants: Ethnopharmacological relevance to modern perspectives
title_fullStr Drugs from poisonous plants: Ethnopharmacological relevance to modern perspectives
title_full_unstemmed Drugs from poisonous plants: Ethnopharmacological relevance to modern perspectives
title_short Drugs from poisonous plants: Ethnopharmacological relevance to modern perspectives
title_sort drugs from poisonous plants ethnopharmacological relevance to modern perspectives
topic Poisonous plants
Therapeutic agents
Phytochemicals
Traditional medicine
url http://www.sciencedirect.com/science/article/pii/S2590171025000025
work_keys_str_mv AT bhagyalakhmirajbongshi drugsfrompoisonousplantsethnopharmacologicalrelevancetomodernperspectives
AT ashiskmukherjee drugsfrompoisonousplantsethnopharmacologicalrelevancetomodernperspectives