Biopolymer crosslinking: Application and prospects
Crosslinking is a method of linking together high-molecular compounds by forming new chemical cross linkages inside and between macrochains. At the same time, various agents can act as cross linkers, i.e., chemical compounds, ultraviolet radiation, etc. Crosslinking of biotissues is known for improv...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Bashkir State Medical University
2025-04-01
|
| Series: | Креативная хирургия и онкология |
| Subjects: | |
| Online Access: | https://www.surgonco.ru/jour/article/view/1052 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849394474075029504 |
|---|---|
| author | M. M. Bikbov I. R. Kabirov A. R. Khalimov A. D. Neryakhin P. N. Shmelkova D. Kh. Gainullina L. S. Gumerova A. A. Tukhbatullin A. A. Akhunzyanov E. A. Nadezhdina |
| author_facet | M. M. Bikbov I. R. Kabirov A. R. Khalimov A. D. Neryakhin P. N. Shmelkova D. Kh. Gainullina L. S. Gumerova A. A. Tukhbatullin A. A. Akhunzyanov E. A. Nadezhdina |
| author_sort | M. M. Bikbov |
| collection | DOAJ |
| description | Crosslinking is a method of linking together high-molecular compounds by forming new chemical cross linkages inside and between macrochains. At the same time, various agents can act as cross linkers, i.e., chemical compounds, ultraviolet radiation, etc. Crosslinking of biotissues is known for improving their mechanical strength, increasing structural density, and reducing bioscaffold permeability. This review aims to characterize possible applications of cross-linking technology in various branches of medicine, i.e., ophthalmology, traumatology, urology, gastroenterology, oncology, bioengineering, and others. A review of domestic and foreign publications was carried out using the database and resources of search systems of scientific electronic libraries such as PubMed, elibrary.ru, Google Scholar, Science Direct, and the library stock of Bashkir State Medical University for the period from 1994 to 2023. The study of available literature sources makes it possible to conclude that the method of ultraviolet crosslinking is currently widely used in ophthalmology, while various modifications of crosslinking have prospects in medicine and related industries and can become the basis for the creation of bioengineered products and original medical technologies aimed at improving the effectiveness of treatment of various human diseases. |
| format | Article |
| id | doaj-art-922d861dcbbc4437b126ba0660b6328c |
| institution | Kabale University |
| issn | 2076-3093 2307-0501 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Bashkir State Medical University |
| record_format | Article |
| series | Креативная хирургия и онкология |
| spelling | doaj-art-922d861dcbbc4437b126ba0660b6328c2025-08-20T03:39:58ZengBashkir State Medical UniversityКреативная хирургия и онкология2076-30932307-05012025-04-01151505610.24060/2076-3093-2025-15-1-50-56613Biopolymer crosslinking: Application and prospectsM. M. Bikbov0I. R. Kabirov1A. R. Khalimov2A. D. Neryakhin3P. N. Shmelkova4D. Kh. Gainullina5L. S. Gumerova6A. A. Tukhbatullin7A. A. Akhunzyanov8E. A. Nadezhdina9Ufa Eye Research Institute, Bashkir State Medical UniversityBashkir State Medical UniversityUfa Eye Research Institute, Bashkir State Medical UniversityBashkir State Medical UniversityBashkir State Medical UniversityBashkir State Medical UniversityBashkir State Medical UniversityBashkir State Medical UniversityBashkir State Medical UniversityBashkir State Medical UniversityCrosslinking is a method of linking together high-molecular compounds by forming new chemical cross linkages inside and between macrochains. At the same time, various agents can act as cross linkers, i.e., chemical compounds, ultraviolet radiation, etc. Crosslinking of biotissues is known for improving their mechanical strength, increasing structural density, and reducing bioscaffold permeability. This review aims to characterize possible applications of cross-linking technology in various branches of medicine, i.e., ophthalmology, traumatology, urology, gastroenterology, oncology, bioengineering, and others. A review of domestic and foreign publications was carried out using the database and resources of search systems of scientific electronic libraries such as PubMed, elibrary.ru, Google Scholar, Science Direct, and the library stock of Bashkir State Medical University for the period from 1994 to 2023. The study of available literature sources makes it possible to conclude that the method of ultraviolet crosslinking is currently widely used in ophthalmology, while various modifications of crosslinking have prospects in medicine and related industries and can become the basis for the creation of bioengineered products and original medical technologies aimed at improving the effectiveness of treatment of various human diseases.https://www.surgonco.ru/jour/article/view/1052crosslinkingpolymerscollagenbioprintinghydrogelcrosslinking reagentsbiocompatible materials |
| spellingShingle | M. M. Bikbov I. R. Kabirov A. R. Khalimov A. D. Neryakhin P. N. Shmelkova D. Kh. Gainullina L. S. Gumerova A. A. Tukhbatullin A. A. Akhunzyanov E. A. Nadezhdina Biopolymer crosslinking: Application and prospects Креативная хирургия и онкология crosslinking polymers collagen bioprinting hydrogel crosslinking reagents biocompatible materials |
| title | Biopolymer crosslinking: Application and prospects |
| title_full | Biopolymer crosslinking: Application and prospects |
| title_fullStr | Biopolymer crosslinking: Application and prospects |
| title_full_unstemmed | Biopolymer crosslinking: Application and prospects |
| title_short | Biopolymer crosslinking: Application and prospects |
| title_sort | biopolymer crosslinking application and prospects |
| topic | crosslinking polymers collagen bioprinting hydrogel crosslinking reagents biocompatible materials |
| url | https://www.surgonco.ru/jour/article/view/1052 |
| work_keys_str_mv | AT mmbikbov biopolymercrosslinkingapplicationandprospects AT irkabirov biopolymercrosslinkingapplicationandprospects AT arkhalimov biopolymercrosslinkingapplicationandprospects AT adneryakhin biopolymercrosslinkingapplicationandprospects AT pnshmelkova biopolymercrosslinkingapplicationandprospects AT dkhgainullina biopolymercrosslinkingapplicationandprospects AT lsgumerova biopolymercrosslinkingapplicationandprospects AT aatukhbatullin biopolymercrosslinkingapplicationandprospects AT aaakhunzyanov biopolymercrosslinkingapplicationandprospects AT eanadezhdina biopolymercrosslinkingapplicationandprospects |