Ginsenoside Ro ameliorates cognitive impairment and neuroinflammation in APP/PS1 mice via the IBA1/GFAP-MAPK signaling pathway

Ginsenoside Ro ameliorates cognitive impairment and neuroinflammation in APP/PS1 mice via the IBA1/GFAP-MAPK signaling pathway

IntroductionGinseng, known as the “king of herbs,” has long been used in traditional Chinese medicine due to its beneficial properties, including anti-aging, anti-inflammatory, and anti-apoptotic effects. Ginsenosides, the active compounds in ginseng, have shown promise in treating neurodegenerative...

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Bibliographic Details
Main Authors: Tianyao Li, Jiaxin Chen, Zhouyuan Xie, Jiansong Fang, Qiqing Wu, Xinyue Cao, Ziying Chen, Yiyun Wang, Qiqi Fan, Qi Wang, Jinman Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pharmacology
Subjects:
Alzheimer’s disease
APP/PS1 mice
Ginsenoside Ro
neuronal apoptosis
neuroinflammation
IBA1/GFAP-MAPK pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1528590/full
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