Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation

Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation

Early-life stress can have lifelong consequences, enhancing stress susceptibility and resulting in behavioural and cognitive deficits. While the effects of early-life stress on neuronal function have been well-described, we still know very little about the contribution of non-neuronal brain cells. I...

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Bibliographic Details
Main Authors: Mathias Guayasamin, Lewis R Depaauw-Holt, Ifeoluwa I Adedipe, Ossama Ghenissa, Juliette Vaugeois, Manon Duquenne, Benjamin Rogers, Jade Latraverse-Arquilla, Sarah Peyrard, Anthony Bosson, Ciaran Murphy-Royal
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-02-01
Series:eLife
Subjects:
glial cell
astrocytes
early-life stress
engram
learning and memory
neuron–glia interactions
Online Access:https://elifesciences.org/articles/99988
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