Testing for HIV infection in the emergency departments of 2 hospitals in the Southeastern United States

Abstract Background In 2006, the Centers for Disease Control and Prevention (CDC) recommended non‐targeted, opt‐out HIV screening in all healthcare settings, including emergency departments (EDs). Multiple HIV testing programs have been implemented in EDs across the United States with varying design...

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Main Authors: Rachel Safeek, Tamsey Hill, Arthur Hendricks, David Underwood, Mary Washington, Jessica Guidici, Tammy Wong, Charles Gerardo, Charles Hicks, Mehri McKellar
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Journal of the American College of Emergency Physicians Open
Subjects:
Online Access:https://doi.org/10.1002/emp2.12102
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author Rachel Safeek
Tamsey Hill
Arthur Hendricks
David Underwood
Mary Washington
Jessica Guidici
Tammy Wong
Charles Gerardo
Charles Hicks
Mehri McKellar
author_facet Rachel Safeek
Tamsey Hill
Arthur Hendricks
David Underwood
Mary Washington
Jessica Guidici
Tammy Wong
Charles Gerardo
Charles Hicks
Mehri McKellar
author_sort Rachel Safeek
collection DOAJ
description Abstract Background In 2006, the Centers for Disease Control and Prevention (CDC) recommended non‐targeted, opt‐out HIV screening in all healthcare settings, including emergency departments (EDs). Multiple HIV testing programs have been implemented in EDs across the United States with varying designs and testing platforms. We report findings from a free, non‐targeted, rapid HIV testing program in 2 EDs in the Southeastern United States. Methods From 2008 to 2012, adults ≥18 years of age were offered free rapid HIV testing using an oral swab test (OraQuick ADVANCE Rapid HIV‐1/2 antibody test) in the EDs of a large academic medical center and an affiliated community hospital in Durham, North Carolina. Results In total, 5443 ED patients were offered HIV testing. The overall acceptance rate was 66.9% (3639/5443). Younger persons were significantly more likely to accept testing (78.2% for 18–29 years old vs 67.1% for ≥30 years old; P < 0.001) as were Black participants (72.6% Black vs 66.5% White; P < 0.001). Acceptance rates improved significantly after opt‐out oral consent replaced written consent (71.3% vs 63.1%; P < 0.001). Seven new HIV diagnoses were confirmed during the testing program, resulting in a seropositivity rate of 0.19% (7/3639). There were 8 false–positive rapid oral HIV tests (positive predictive value = 46.7%). Conclusions Although the number of new HIV diagnoses was low, implementation of this rapid, non‐targeted ED screening program was feasible with high acceptance rates, particularly after introducing the opt‐out oral consent approach.
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spelling doaj-art-92241b1a2b2b42488bfec83945f1ae672025-08-20T03:49:08ZengElsevierJournal of the American College of Emergency Physicians Open2688-11522020-08-011448749310.1002/emp2.12102Testing for HIV infection in the emergency departments of 2 hospitals in the Southeastern United StatesRachel Safeek0Tamsey Hill1Arthur Hendricks2David Underwood3Mary Washington4Jessica Guidici5Tammy Wong6Charles Gerardo7Charles Hicks8Mehri McKellar9University of Louisville School of Medicine Louisville Kentucky USAPastoral Services Duke University Durham North Carolina USAPastoral Services Duke University Durham North Carolina USAPastoral Services Duke University Durham North Carolina USAPastoral Services Duke University Durham North Carolina USADivision of Infectious Diseases Duke University Durham North Carolina USADivision of Infectious Diseases Duke University Durham North Carolina USADivision of Emergency Medicine Duke University Durham North Carolina USAViiV Healthcare Research Triangle North Carolina USADuke University Durham North Carolina USAAbstract Background In 2006, the Centers for Disease Control and Prevention (CDC) recommended non‐targeted, opt‐out HIV screening in all healthcare settings, including emergency departments (EDs). Multiple HIV testing programs have been implemented in EDs across the United States with varying designs and testing platforms. We report findings from a free, non‐targeted, rapid HIV testing program in 2 EDs in the Southeastern United States. Methods From 2008 to 2012, adults ≥18 years of age were offered free rapid HIV testing using an oral swab test (OraQuick ADVANCE Rapid HIV‐1/2 antibody test) in the EDs of a large academic medical center and an affiliated community hospital in Durham, North Carolina. Results In total, 5443 ED patients were offered HIV testing. The overall acceptance rate was 66.9% (3639/5443). Younger persons were significantly more likely to accept testing (78.2% for 18–29 years old vs 67.1% for ≥30 years old; P < 0.001) as were Black participants (72.6% Black vs 66.5% White; P < 0.001). Acceptance rates improved significantly after opt‐out oral consent replaced written consent (71.3% vs 63.1%; P < 0.001). Seven new HIV diagnoses were confirmed during the testing program, resulting in a seropositivity rate of 0.19% (7/3639). There were 8 false–positive rapid oral HIV tests (positive predictive value = 46.7%). Conclusions Although the number of new HIV diagnoses was low, implementation of this rapid, non‐targeted ED screening program was feasible with high acceptance rates, particularly after introducing the opt‐out oral consent approach.https://doi.org/10.1002/emp2.12102acceptance ratesemergency departmentHIVHIV testingnon‐targetedrapid
spellingShingle Rachel Safeek
Tamsey Hill
Arthur Hendricks
David Underwood
Mary Washington
Jessica Guidici
Tammy Wong
Charles Gerardo
Charles Hicks
Mehri McKellar
Testing for HIV infection in the emergency departments of 2 hospitals in the Southeastern United States
Journal of the American College of Emergency Physicians Open
acceptance rates
emergency department
HIV
HIV testing
non‐targeted
rapid
title Testing for HIV infection in the emergency departments of 2 hospitals in the Southeastern United States
title_full Testing for HIV infection in the emergency departments of 2 hospitals in the Southeastern United States
title_fullStr Testing for HIV infection in the emergency departments of 2 hospitals in the Southeastern United States
title_full_unstemmed Testing for HIV infection in the emergency departments of 2 hospitals in the Southeastern United States
title_short Testing for HIV infection in the emergency departments of 2 hospitals in the Southeastern United States
title_sort testing for hiv infection in the emergency departments of 2 hospitals in the southeastern united states
topic acceptance rates
emergency department
HIV
HIV testing
non‐targeted
rapid
url https://doi.org/10.1002/emp2.12102
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