Effects of Glucomannan on the Sacculus Rotundus and Peripheral Blood Lymphocytes in New Zealand Rabbits during Aflatoxicosis

This study was aimed to determine the effects of the glucomannan added to aflatoxin- (AF-) contaminated diet on the sacculus rotundus and peripheral blood lymphocytes of New Zealand rabbits by histological and enzyme histochemical methods. Twenty-four adult rabbits of both sexes were divided into fo...

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Main Authors: Emrah Sur, Hasan Hüseyin Dönmez, Murat Boydak, Mehmet Bozkurt Ataman
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2012/632945
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author Emrah Sur
Hasan Hüseyin Dönmez
Murat Boydak
Mehmet Bozkurt Ataman
author_facet Emrah Sur
Hasan Hüseyin Dönmez
Murat Boydak
Mehmet Bozkurt Ataman
author_sort Emrah Sur
collection DOAJ
description This study was aimed to determine the effects of the glucomannan added to aflatoxin- (AF-) contaminated diet on the sacculus rotundus and peripheral blood lymphocytes of New Zealand rabbits by histological and enzyme histochemical methods. Twenty-four adult rabbits of both sexes were divided into four equal groups, namely, as control, glucomannan 0.2 g/day, AF 125 μg/kg/day, and glucomannan combined with AF. The animals in all groups were treated for 12 weeks by the above-mentioned diet. When compared to control, AF-treatment caused significant decrease in alpha-naphthyl acetate esterase- (ANAE-) positive peripheral blood lymphocyte (PBL) percentages. The addition of the glucomannan to AFcontaining diet recovered the adverse effects of AF on sacculus rotundus and increased the ANAE-positive PBL counts. These results suggested that glucomannan was effective against the negative effects of AF in rabbits.
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institution Kabale University
issn 1537-744X
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-921558f6fa784b42bcd0e1d0ee606d6d2025-02-03T01:22:14ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/632945632945Effects of Glucomannan on the Sacculus Rotundus and Peripheral Blood Lymphocytes in New Zealand Rabbits during AflatoxicosisEmrah Sur0Hasan Hüseyin Dönmez1Murat Boydak2Mehmet Bozkurt Ataman3Department of Histology, Selçuk University Veterinary Faculty, 42031 Konya, TurkeyDepartment of Histology, Faculty of Veterinary Medicine, University of Kyrgyzstan-Turkey Manas, Bishkek, KyrgyzstanDepartment of Histology, Selçuk University Veterinary Faculty, 42031 Konya, TurkeyDepartment of Reproduction and Artificial Insemination, Selçuk University Veterinary Faculty, 42031 Konya, TurkeyThis study was aimed to determine the effects of the glucomannan added to aflatoxin- (AF-) contaminated diet on the sacculus rotundus and peripheral blood lymphocytes of New Zealand rabbits by histological and enzyme histochemical methods. Twenty-four adult rabbits of both sexes were divided into four equal groups, namely, as control, glucomannan 0.2 g/day, AF 125 μg/kg/day, and glucomannan combined with AF. The animals in all groups were treated for 12 weeks by the above-mentioned diet. When compared to control, AF-treatment caused significant decrease in alpha-naphthyl acetate esterase- (ANAE-) positive peripheral blood lymphocyte (PBL) percentages. The addition of the glucomannan to AFcontaining diet recovered the adverse effects of AF on sacculus rotundus and increased the ANAE-positive PBL counts. These results suggested that glucomannan was effective against the negative effects of AF in rabbits.http://dx.doi.org/10.1100/2012/632945
spellingShingle Emrah Sur
Hasan Hüseyin Dönmez
Murat Boydak
Mehmet Bozkurt Ataman
Effects of Glucomannan on the Sacculus Rotundus and Peripheral Blood Lymphocytes in New Zealand Rabbits during Aflatoxicosis
The Scientific World Journal
title Effects of Glucomannan on the Sacculus Rotundus and Peripheral Blood Lymphocytes in New Zealand Rabbits during Aflatoxicosis
title_full Effects of Glucomannan on the Sacculus Rotundus and Peripheral Blood Lymphocytes in New Zealand Rabbits during Aflatoxicosis
title_fullStr Effects of Glucomannan on the Sacculus Rotundus and Peripheral Blood Lymphocytes in New Zealand Rabbits during Aflatoxicosis
title_full_unstemmed Effects of Glucomannan on the Sacculus Rotundus and Peripheral Blood Lymphocytes in New Zealand Rabbits during Aflatoxicosis
title_short Effects of Glucomannan on the Sacculus Rotundus and Peripheral Blood Lymphocytes in New Zealand Rabbits during Aflatoxicosis
title_sort effects of glucomannan on the sacculus rotundus and peripheral blood lymphocytes in new zealand rabbits during aflatoxicosis
url http://dx.doi.org/10.1100/2012/632945
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