Metabolomic characterisation of the glioblastoma invasive margin reveals a region-specific signature

Metabolomic characterisation of the glioblastoma invasive margin reveals a region-specific signature

Isocitrate dehydrogenase wild-type glioblastoma (GBM) is characterised by a heterogeneous genetic landscape resulting from dynamic competition between tumour subclones to survive selective pressures. Improvements in metabolite identification and metabolome coverage have led to increased interest in...

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Bibliographic Details
Main Authors: James Wood, Stuart J. Smith, Marcos Castellanos-Uribe, Anbarasu Lourdusamy, Sean T. May, David A. Barrett, Richard G. Grundy, Dong-Hyun Kim, Ruman Rahman
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Subjects:
Glioblastoma
Metabolomics
Invasive margin
Liquid-chromatography mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024173409
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