8-Oxo-7,8-dihydro-2′-deoxyguanosine values measured in brain DNA of rats upon investigating cortexin protective action
The protective effect of cortexin was investigated with the use of acoustic stress hemorrhagic stroke model. A significant decrease of 8-oxo-2'-deoxyguanosine to 2'-deoxyguanosine ratio in the DNA molecule was shown using brain slices of cortexin treated Krushinsky-Molodkina rats.
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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MIREA - Russian Technological University
2012-02-01
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| Series: | Тонкие химические технологии |
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| Online Access: | https://www.finechem-mirea.ru/jour/article/view/776 |
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| _version_ | 1849253172192739328 |
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| author | D. S. Esipov O. V. Esipova T. V. Zinevich T. A. Gorbacheva T. S. Nevredimova A. L. Krushinsky V. S. Kuzenkov V. P. Reutov |
| author_facet | D. S. Esipov O. V. Esipova T. V. Zinevich T. A. Gorbacheva T. S. Nevredimova A. L. Krushinsky V. S. Kuzenkov V. P. Reutov |
| author_sort | D. S. Esipov |
| collection | DOAJ |
| description | The protective effect of cortexin was investigated with the use of acoustic stress hemorrhagic stroke model. A significant decrease of 8-oxo-2'-deoxyguanosine to 2'-deoxyguanosine ratio in the DNA molecule was shown using brain slices of cortexin treated Krushinsky-Molodkina rats. |
| format | Article |
| id | doaj-art-920a9079047e4baaa5abbe0ffb408e2d |
| institution | Kabale University |
| issn | 2410-6593 2686-7575 |
| language | Russian |
| publishDate | 2012-02-01 |
| publisher | MIREA - Russian Technological University |
| record_format | Article |
| series | Тонкие химические технологии |
| spelling | doaj-art-920a9079047e4baaa5abbe0ffb408e2d2025-08-20T03:56:24ZrusMIREA - Russian Technological UniversityТонкие химические технологии2410-65932686-75752012-02-017159637708-Oxo-7,8-dihydro-2′-deoxyguanosine values measured in brain DNA of rats upon investigating cortexin protective actionD. S. Esipov0O. V. Esipova1T. V. Zinevich2T. A. Gorbacheva3T. S. Nevredimova4A. L. Krushinsky5V. S. Kuzenkov6V. P. Reutov7МГУ им. М.В. ЛомоносоваM.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571МГУ им. М.В. ЛомоносоваM.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571МГУ им. М.В. ЛомоносоваМГУ им. М.В. ЛомоносоваИнститут высшей нервной деятельности и нейрофизиологии РАНThe protective effect of cortexin was investigated with the use of acoustic stress hemorrhagic stroke model. A significant decrease of 8-oxo-2'-deoxyguanosine to 2'-deoxyguanosine ratio in the DNA molecule was shown using brain slices of cortexin treated Krushinsky-Molodkina rats.https://www.finechem-mirea.ru/jour/article/view/776cortexin8-oxo-2'-deoxyguanosineoxidative stressreverse phase hplcamperometric detectionhemorrhagic strokeacoustic stress |
| spellingShingle | D. S. Esipov O. V. Esipova T. V. Zinevich T. A. Gorbacheva T. S. Nevredimova A. L. Krushinsky V. S. Kuzenkov V. P. Reutov 8-Oxo-7,8-dihydro-2′-deoxyguanosine values measured in brain DNA of rats upon investigating cortexin protective action Тонкие химические технологии cortexin 8-oxo-2'-deoxyguanosine oxidative stress reverse phase hplc amperometric detection hemorrhagic stroke acoustic stress |
| title | 8-Oxo-7,8-dihydro-2′-deoxyguanosine values measured in brain DNA of rats upon investigating cortexin protective action |
| title_full | 8-Oxo-7,8-dihydro-2′-deoxyguanosine values measured in brain DNA of rats upon investigating cortexin protective action |
| title_fullStr | 8-Oxo-7,8-dihydro-2′-deoxyguanosine values measured in brain DNA of rats upon investigating cortexin protective action |
| title_full_unstemmed | 8-Oxo-7,8-dihydro-2′-deoxyguanosine values measured in brain DNA of rats upon investigating cortexin protective action |
| title_short | 8-Oxo-7,8-dihydro-2′-deoxyguanosine values measured in brain DNA of rats upon investigating cortexin protective action |
| title_sort | 8 oxo 7 8 dihydro 2 deoxyguanosine values measured in brain dna of rats upon investigating cortexin protective action |
| topic | cortexin 8-oxo-2'-deoxyguanosine oxidative stress reverse phase hplc amperometric detection hemorrhagic stroke acoustic stress |
| url | https://www.finechem-mirea.ru/jour/article/view/776 |
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