Primary esophageal melanoma: features of diagnosis and treatment
Primary esophageal melanoma is a rare and extremely aggressive malignant neoplasm originating from mucosal melanocytes. The complex histological structure of the tumor, which in 10–25 % of cases may not contain melanin characteristic of these formations, leads to a high frequency of diagnostic error...
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| Format: | Article |
| Language: | Russian |
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Pavlov First Saint Petersburg State Medical University
2023-07-01
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| Series: | Вестник хирургии имени И.И. Грекова |
| Subjects: | |
| Online Access: | https://www.vestnik-grekova.ru/jour/article/view/2036 |
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| author | B. V. Sigua S. Yu. Rakita A. S. Kachiuri D. V. Gurzhy A. V. Belyaeva V. P. Zemlyanoy |
| author_facet | B. V. Sigua S. Yu. Rakita A. S. Kachiuri D. V. Gurzhy A. V. Belyaeva V. P. Zemlyanoy |
| author_sort | B. V. Sigua |
| collection | DOAJ |
| description | Primary esophageal melanoma is a rare and extremely aggressive malignant neoplasm originating from mucosal melanocytes. The complex histological structure of the tumor, which in 10–25 % of cases may not contain melanin characteristic of these formations, leads to a high frequency of diagnostic errors, reaching 50 %. Immunohistochemical examination is the standard for diagnosing the disease. Primary esophageal melanoma is a tumor with a high potential for hematogenous and lymphogenous metastasis. So, when the tumor spreads to the submucosa, the frequency of locoregional metastasis reaches 54 %. Radical surgery in combination with adjuvant methods of treatment improves the results of treatment in this category of patients. Immunotherapy is a promising method of complex treatment, but requires further study. |
| format | Article |
| id | doaj-art-920643bca59b43f4a605bbd513ca1c71 |
| institution | DOAJ |
| issn | 0042-4625 |
| language | Russian |
| publishDate | 2023-07-01 |
| publisher | Pavlov First Saint Petersburg State Medical University |
| record_format | Article |
| series | Вестник хирургии имени И.И. Грекова |
| spelling | doaj-art-920643bca59b43f4a605bbd513ca1c712025-08-20T03:02:29ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252023-07-011816939710.24884/0042-4625-2022-181-6-93-971459Primary esophageal melanoma: features of diagnosis and treatmentB. V. Sigua0S. Yu. Rakita1A. S. Kachiuri2D. V. Gurzhy3A. V. Belyaeva4V. P. Zemlyanoy5North-Western State Medical University named after I. I. MechnikovNorth-Western State Medical University named after I. I. MechnikovNorth-Western State Medical University named after I. I. MechnikovNorth-Western State Medical University named after I. I. MechnikovNorth-Western State Medical University named after I. I. MechnikovNorth-Western State Medical University named after I. I. MechnikovPrimary esophageal melanoma is a rare and extremely aggressive malignant neoplasm originating from mucosal melanocytes. The complex histological structure of the tumor, which in 10–25 % of cases may not contain melanin characteristic of these formations, leads to a high frequency of diagnostic errors, reaching 50 %. Immunohistochemical examination is the standard for diagnosing the disease. Primary esophageal melanoma is a tumor with a high potential for hematogenous and lymphogenous metastasis. So, when the tumor spreads to the submucosa, the frequency of locoregional metastasis reaches 54 %. Radical surgery in combination with adjuvant methods of treatment improves the results of treatment in this category of patients. Immunotherapy is a promising method of complex treatment, but requires further study.https://www.vestnik-grekova.ru/jour/article/view/2036primary esophageal melanomadiagnosistreatmentimmunotherapymucosal melanoma |
| spellingShingle | B. V. Sigua S. Yu. Rakita A. S. Kachiuri D. V. Gurzhy A. V. Belyaeva V. P. Zemlyanoy Primary esophageal melanoma: features of diagnosis and treatment Вестник хирургии имени И.И. Грекова primary esophageal melanoma diagnosis treatment immunotherapy mucosal melanoma |
| title | Primary esophageal melanoma: features of diagnosis and treatment |
| title_full | Primary esophageal melanoma: features of diagnosis and treatment |
| title_fullStr | Primary esophageal melanoma: features of diagnosis and treatment |
| title_full_unstemmed | Primary esophageal melanoma: features of diagnosis and treatment |
| title_short | Primary esophageal melanoma: features of diagnosis and treatment |
| title_sort | primary esophageal melanoma features of diagnosis and treatment |
| topic | primary esophageal melanoma diagnosis treatment immunotherapy mucosal melanoma |
| url | https://www.vestnik-grekova.ru/jour/article/view/2036 |
| work_keys_str_mv | AT bvsigua primaryesophagealmelanomafeaturesofdiagnosisandtreatment AT syurakita primaryesophagealmelanomafeaturesofdiagnosisandtreatment AT askachiuri primaryesophagealmelanomafeaturesofdiagnosisandtreatment AT dvgurzhy primaryesophagealmelanomafeaturesofdiagnosisandtreatment AT avbelyaeva primaryesophagealmelanomafeaturesofdiagnosisandtreatment AT vpzemlyanoy primaryesophagealmelanomafeaturesofdiagnosisandtreatment |