Evaluation of the validity of the nSOFA score in newborns with sepsis

The objective of the study is to evaluate the discriminative ability of nSOFA in newborns with sepsis.Subjects: The study was designed as retrospective, observational, and one-center. End points included assessment of the severity as per nSOFA and pSOFA; 28-day survival. 121 patients were enrolled i...

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Main Authors: P. I. Mironov, A. U. Lekmanov
Format: Article
Language:Russian
Published: New Terra Publishing House 2021-05-01
Series:Вестник анестезиологии и реаниматологии
Subjects:
Online Access:https://www.vair-journal.com/jour/article/view/515
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author P. I. Mironov
A. U. Lekmanov
author_facet P. I. Mironov
A. U. Lekmanov
author_sort P. I. Mironov
collection DOAJ
description The objective of the study is to evaluate the discriminative ability of nSOFA in newborns with sepsis.Subjects: The study was designed as retrospective, observational, and one-center. End points included assessment of the severity as per nSOFA and pSOFA; 28-day survival. 121 patients were enrolled in the study. Microsoft Excel (Graphpad Software, San Diego, California, USA) and MedCalc (v 7.1.0.0; MedCalc Software, Belgium) were used for the analysis.Results. A study of the discriminative power of the scores showed that both assessment systems had a good model quality. However, nSOFA had a statistically more significant (p < 0.05) area under the ROC curve (0.981± 0.014).Conclusion. The high value of the discriminative ability of the nSOFA scale indicates the feasibility of its use in patients with sepsis in neonatal intensive care units
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issn 2078-5658
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series Вестник анестезиологии и реаниматологии
spelling doaj-art-9205de4a84244fa0b6ee2bf9c9645c382025-08-20T03:42:48ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532021-05-01182566110.21292/2078-5658-2021-18-2-56-61439Evaluation of the validity of the nSOFA score in newborns with sepsisP. I. Mironov0A. U. Lekmanov1Bashkortostan State Medical UniversityClinical Surgery Research Institute by Pirogov Russian National Research Medical UniversityThe objective of the study is to evaluate the discriminative ability of nSOFA in newborns with sepsis.Subjects: The study was designed as retrospective, observational, and one-center. End points included assessment of the severity as per nSOFA and pSOFA; 28-day survival. 121 patients were enrolled in the study. Microsoft Excel (Graphpad Software, San Diego, California, USA) and MedCalc (v 7.1.0.0; MedCalc Software, Belgium) were used for the analysis.Results. A study of the discriminative power of the scores showed that both assessment systems had a good model quality. However, nSOFA had a statistically more significant (p < 0.05) area under the ROC curve (0.981± 0.014).Conclusion. The high value of the discriminative ability of the nSOFA scale indicates the feasibility of its use in patients with sepsis in neonatal intensive care unitshttps://www.vair-journal.com/jour/article/view/515newbornsseverity of the conditionnsofa, validity
spellingShingle P. I. Mironov
A. U. Lekmanov
Evaluation of the validity of the nSOFA score in newborns with sepsis
Вестник анестезиологии и реаниматологии
newborns
severity of the condition
nsofa, validity
title Evaluation of the validity of the nSOFA score in newborns with sepsis
title_full Evaluation of the validity of the nSOFA score in newborns with sepsis
title_fullStr Evaluation of the validity of the nSOFA score in newborns with sepsis
title_full_unstemmed Evaluation of the validity of the nSOFA score in newborns with sepsis
title_short Evaluation of the validity of the nSOFA score in newborns with sepsis
title_sort evaluation of the validity of the nsofa score in newborns with sepsis
topic newborns
severity of the condition
nsofa, validity
url https://www.vair-journal.com/jour/article/view/515
work_keys_str_mv AT pimironov evaluationofthevalidityofthensofascoreinnewbornswithsepsis
AT aulekmanov evaluationofthevalidityofthensofascoreinnewbornswithsepsis