A Single-Centre Experience of Post-COVID-19 Vaccine-Related Immune-Mediated Complications

The significant impact of the COVID-19 pandemic has resulted in a worldwide effort to develop effective vaccines. In the United Kingdom, the COVID-19 vaccine development and roll-out has been overwhelmingly successful in reducing infections and deaths. However, case reports have emerged of a rare sy...

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Main Authors: David Palmer, Lauren Davis, Helena Sivaloganathan, Timothy Chevassut
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2022/4742639
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author David Palmer
Lauren Davis
Helena Sivaloganathan
Timothy Chevassut
author_facet David Palmer
Lauren Davis
Helena Sivaloganathan
Timothy Chevassut
author_sort David Palmer
collection DOAJ
description The significant impact of the COVID-19 pandemic has resulted in a worldwide effort to develop effective vaccines. In the United Kingdom, the COVID-19 vaccine development and roll-out has been overwhelmingly successful in reducing infections and deaths. However, case reports have emerged of a rare syndrome of vaccine-induced immune thrombocytopenia and thrombosis (VITT), as well as cases of immune thrombocytopenia (ITP). This has necessitated a better understanding of these conditions. However, as both VITT and “vaccine-associated ITP” are emerging conditions, evidence on the clinical features, epidemiology, and management is still evolving. Subsequently, with the initiation of the COVID-19 vaccine booster program, it has become increasingly important to continue to collect accurate data on post-COVID-19 vaccine complications to aid with their prompt recognition and management. In this case series, we report on the presentations and management of seven cases of post-COVID-19 vaccine-related immune-mediated complications which occurred at our center between the months of March and July 2021.
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spelling doaj-art-91ff52cb47124352aa5e16deb918e1142025-08-20T03:37:08ZengWileyCase Reports in Hematology2090-65792022-01-01202210.1155/2022/4742639A Single-Centre Experience of Post-COVID-19 Vaccine-Related Immune-Mediated ComplicationsDavid Palmer0Lauren Davis1Helena Sivaloganathan2Timothy Chevassut3Royal Sussex County HospitalsRoyal Sussex County HospitalsRoyal Sussex County HospitalsRoyal Sussex County HospitalsThe significant impact of the COVID-19 pandemic has resulted in a worldwide effort to develop effective vaccines. In the United Kingdom, the COVID-19 vaccine development and roll-out has been overwhelmingly successful in reducing infections and deaths. However, case reports have emerged of a rare syndrome of vaccine-induced immune thrombocytopenia and thrombosis (VITT), as well as cases of immune thrombocytopenia (ITP). This has necessitated a better understanding of these conditions. However, as both VITT and “vaccine-associated ITP” are emerging conditions, evidence on the clinical features, epidemiology, and management is still evolving. Subsequently, with the initiation of the COVID-19 vaccine booster program, it has become increasingly important to continue to collect accurate data on post-COVID-19 vaccine complications to aid with their prompt recognition and management. In this case series, we report on the presentations and management of seven cases of post-COVID-19 vaccine-related immune-mediated complications which occurred at our center between the months of March and July 2021.http://dx.doi.org/10.1155/2022/4742639
spellingShingle David Palmer
Lauren Davis
Helena Sivaloganathan
Timothy Chevassut
A Single-Centre Experience of Post-COVID-19 Vaccine-Related Immune-Mediated Complications
Case Reports in Hematology
title A Single-Centre Experience of Post-COVID-19 Vaccine-Related Immune-Mediated Complications
title_full A Single-Centre Experience of Post-COVID-19 Vaccine-Related Immune-Mediated Complications
title_fullStr A Single-Centre Experience of Post-COVID-19 Vaccine-Related Immune-Mediated Complications
title_full_unstemmed A Single-Centre Experience of Post-COVID-19 Vaccine-Related Immune-Mediated Complications
title_short A Single-Centre Experience of Post-COVID-19 Vaccine-Related Immune-Mediated Complications
title_sort single centre experience of post covid 19 vaccine related immune mediated complications
url http://dx.doi.org/10.1155/2022/4742639
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