Research on the quality supervision strategy of drugs sold on the internet under the MAH system
BackgroundIn recent years, purchasing medications online has become increasingly popular. However, occasional quality issues have arisen with drugs bought online. As a result, we need effective quality monitoring of medicines sold online. To address this issues, several countries have begun to imple...
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Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1457340/full |
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| author | Zongliang Wen Zongliang Wen Zongliang Wen Jialin Chen Li Zhou Li Zhou Long Bai Shenqin Wu Yun Zhao Yun Zhao Jinhua Fang |
| author_facet | Zongliang Wen Zongliang Wen Zongliang Wen Jialin Chen Li Zhou Li Zhou Long Bai Shenqin Wu Yun Zhao Yun Zhao Jinhua Fang |
| author_sort | Zongliang Wen |
| collection | DOAJ |
| description | BackgroundIn recent years, purchasing medications online has become increasingly popular. However, occasional quality issues have arisen with drugs bought online. As a result, we need effective quality monitoring of medicines sold online. To address this issues, several countries have begun to implement the Marketing Authorization Holder (MAH) system to enhance drug quality control.MethodsConsequently, this paper develops a four-party evolutionary game model that includes the government, holder, agent seller and third-party platform in pharmaceutical online sales, and use Matlab 2022b to carry out numerical simulation, and to compare and analyze the influence of different factors on the strategy selection of the main body of the game by changing parameters. This paper is based on the multi-party game perspective, constructed a hierarchical model, thereby better exploring the mechanism of drug quality regulation in the context of drug online sales under the MAH system.ResultsFindings suggest that reducing operational costs motivates agent sellers to adopt stable, honest strategies. Increased government penalties expedite the adoption of positive strategies by sellers, holders, and third-party platforms. Enhanced penalties from holders and platforms for defaults effectively regulate seller behavior. Additionally, reputation rewards or losses incentivize sellers to adopt honest practices, with consumer and sellers' reputations influencing the likelihood of comprehensive third-party platform reviews.ConclusionsIn summary, policy makers should improve the regulatory mechanism, establish a fair system of rewards and penalties, develop a compensation mechanism for information sharing, deregulate prices and enhancing feedback channels. |
| format | Article |
| id | doaj-art-91f798e15c1c46e39443eb007cd7cf0b |
| institution | DOAJ |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj-art-91f798e15c1c46e39443eb007cd7cf0b2025-08-20T03:06:13ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-04-011310.3389/fpubh.2025.14573401457340Research on the quality supervision strategy of drugs sold on the internet under the MAH systemZongliang Wen0Zongliang Wen1Zongliang Wen2Jialin Chen3Li Zhou4Li Zhou5Long Bai6Shenqin Wu7Yun Zhao8Yun Zhao9Jinhua Fang10School of Management, Xuzhou Medical University, Xuzhou, ChinaInstitution of Chinese Health Modernization, Xuzhou Medical University, Xuzhou, ChinaAffiliated Hospital of Xuzhou Medical University, Xuzhou, ChinaSchool of Management, Xuzhou Medical University, Xuzhou, ChinaSchool of Management, Xuzhou Medical University, Xuzhou, ChinaSchool of Public Health, Nanjing Medical University, Nanjing, ChinaSchool of Public Health, Xuzhou Medical University, Xuzhou, ChinaSchool of Management, Xuzhou Medical University, Xuzhou, ChinaSchool of Management, Xuzhou Medical University, Xuzhou, ChinaInstitution of Chinese Health Modernization, Xuzhou Medical University, Xuzhou, ChinaSchool of Management, Xuzhou Medical University, Xuzhou, ChinaBackgroundIn recent years, purchasing medications online has become increasingly popular. However, occasional quality issues have arisen with drugs bought online. As a result, we need effective quality monitoring of medicines sold online. To address this issues, several countries have begun to implement the Marketing Authorization Holder (MAH) system to enhance drug quality control.MethodsConsequently, this paper develops a four-party evolutionary game model that includes the government, holder, agent seller and third-party platform in pharmaceutical online sales, and use Matlab 2022b to carry out numerical simulation, and to compare and analyze the influence of different factors on the strategy selection of the main body of the game by changing parameters. This paper is based on the multi-party game perspective, constructed a hierarchical model, thereby better exploring the mechanism of drug quality regulation in the context of drug online sales under the MAH system.ResultsFindings suggest that reducing operational costs motivates agent sellers to adopt stable, honest strategies. Increased government penalties expedite the adoption of positive strategies by sellers, holders, and third-party platforms. Enhanced penalties from holders and platforms for defaults effectively regulate seller behavior. Additionally, reputation rewards or losses incentivize sellers to adopt honest practices, with consumer and sellers' reputations influencing the likelihood of comprehensive third-party platform reviews.ConclusionsIn summary, policy makers should improve the regulatory mechanism, establish a fair system of rewards and penalties, develop a compensation mechanism for information sharing, deregulate prices and enhancing feedback channels.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1457340/fulldrug quality supervisionMAH systemonline sales of drugsevolutionary gamesimulation analysis |
| spellingShingle | Zongliang Wen Zongliang Wen Zongliang Wen Jialin Chen Li Zhou Li Zhou Long Bai Shenqin Wu Yun Zhao Yun Zhao Jinhua Fang Research on the quality supervision strategy of drugs sold on the internet under the MAH system Frontiers in Public Health drug quality supervision MAH system online sales of drugs evolutionary game simulation analysis |
| title | Research on the quality supervision strategy of drugs sold on the internet under the MAH system |
| title_full | Research on the quality supervision strategy of drugs sold on the internet under the MAH system |
| title_fullStr | Research on the quality supervision strategy of drugs sold on the internet under the MAH system |
| title_full_unstemmed | Research on the quality supervision strategy of drugs sold on the internet under the MAH system |
| title_short | Research on the quality supervision strategy of drugs sold on the internet under the MAH system |
| title_sort | research on the quality supervision strategy of drugs sold on the internet under the mah system |
| topic | drug quality supervision MAH system online sales of drugs evolutionary game simulation analysis |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1457340/full |
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