Increased TLR4 expression and downstream cytokine production in immunosuppressed adults compared to non-immunosuppressed adults.

Increased TLR4 expression and downstream cytokine production in immunosuppressed adults compared to non-immunosuppressed adults.

<h4>Background</h4>An increasing number of patients have medical conditions with altered host immunity or that require immunosuppressive medications. While immunosuppression is associated with increased risk of infection, the precise effect of immunosuppression on innate immunity is not...

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Main Authors: Dana W Dunne, Albert Shaw, Linda K Bockenstedt, Heather G Allore, Shu Chen, Stephen E Malawista, Lin Leng, Yuka Mizue, Marta Piecychna, Lin Zhang, Virginia Towle, Richard Bucala, Ruth R Montgomery, Erol Fikrig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0011343&type=printable
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