Case Report: Histological Transformation to Atypical Carcinoid in RET Fusion-positive NSCLC Following Immune Therapy Resistance

Case Report: Histological Transformation to Atypical Carcinoid in RET Fusion-positive NSCLC Following Immune Therapy Resistance

Immune checkpoint inhibitors (ICIs) have become the cornerstone of treatment for driver gene-negative advanced non-small cell lung cancer (NSCLC). However, resistance is inevitable, and the underlying mechanisms remain incompletely understood. Histological transformation is a rare but emerging cause...

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Bibliographic Details
Main Authors: Yu ZHANG, Hui ZHANG, Wei ZHONG, Minjiang CHEN, Mengzhao WANG
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2025-05-01
Series:Chinese Journal of Lung Cancer
Subjects:
lung neoplasms
immune resistance
histological transformation
atypical carcinoid
selective ret inhibitors
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2025.102.14
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