Push-pull effects of basal ganglia network in Parkinson’s disease inferred by functional MRI

Push-pull effects of basal ganglia network in Parkinson’s disease inferred by functional MRI

Abstract Deep brain stimulation (DBS) can ameliorate motor symptoms in Parkinson’s disease (PD), but its mechanism remains unclear. This work constructs a multi-scale brain model using the fMRI data from 27 PD patients with subthalamic DBS and 30 healthy controls. The model fits microscopic coupling...

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Bibliographic Details
Main Authors: Yuxin Wang, Zhiqi Jiang, Chunguang Chu, Zhen Zhang, Jiang Wang, Dianyou Li, Naying He, Chris Fietkiewicz, Changsong Zhou, Marcus Kaiser, Xuze Bai, Chencheng Zhang, Chen Liu
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-024-00835-7
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