Patient and Physician Perspectives of Treatment Burden in Multiple Sclerosis
Abstract The number of disease-modifying therapies (DMTs) approved for the treatment of multiple sclerosis (MS) has greatly increased in recent decades, leading to higher treatment complexity. DMTs can differ in mode and frequency of administration, benefit–risk profile, and associated costs. Patien...
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| Format: | Article |
| Language: | English |
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Adis, Springer Healthcare
2024-09-01
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| Series: | Neurology and Therapy |
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| Online Access: | https://doi.org/10.1007/s40120-024-00654-1 |
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| _version_ | 1850061674965368832 |
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| author | Barry A. Singer Dawn Morgan Julie A. Stamm Anita A. Williams |
| author_facet | Barry A. Singer Dawn Morgan Julie A. Stamm Anita A. Williams |
| author_sort | Barry A. Singer |
| collection | DOAJ |
| description | Abstract The number of disease-modifying therapies (DMTs) approved for the treatment of multiple sclerosis (MS) has greatly increased in recent decades, leading to higher treatment complexity. DMTs can differ in mode and frequency of administration, benefit–risk profile, and associated costs. Patients with MS contend not only with the burden of their chronic disease but also with the treatment burden of their MS therapy. Adhering to dosing schedules and infusion appointments can be difficult for busy, working-age patients or those with limited access to transportation. Patients and healthcare professionals (HCPs) may have differing priorities, concerns, and preferences when selecting treatment, potentially affecting treatment satisfaction and, importantly, adherence. Additionally, patients face direct and indirect costs related to treatment. These factors can all contribute to a high treatment burden on patients, impacting their quality of life and potentially leading to worse patient outcomes. HCPs, patients, and caregivers must work together to alleviate treatment burden through effective communication, shared decision-making, appreciating each other’s perspectives, and additional HCP support. Consideration of treatment burden into clinical guidelines is also warranted. In this review, we examine key factors impacting treatment burden for patients with MS, with a focus on the patient perspective as provided by our patient authors, and provide strategies to minimize treatment burden. |
| format | Article |
| id | doaj-art-91d4d5f84d1c472cb202aba7b8c27a05 |
| institution | DOAJ |
| issn | 2193-8253 2193-6536 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Adis, Springer Healthcare |
| record_format | Article |
| series | Neurology and Therapy |
| spelling | doaj-art-91d4d5f84d1c472cb202aba7b8c27a052025-08-20T02:50:08ZengAdis, Springer HealthcareNeurology and Therapy2193-82532193-65362024-09-011361507152510.1007/s40120-024-00654-1Patient and Physician Perspectives of Treatment Burden in Multiple SclerosisBarry A. Singer0Dawn Morgan1Julie A. Stamm2Anita A. Williams3The MS Center for Innovations in Care, Missouri Baptist Medical CenterPatient Author: MS patient advocate, author, speaker, founder of Unquiet Minds Move NonprofitPatient Author: MS patient advocate, author, educatorPatient Author: MS patient advocate, author, co-founder of MS Minority Research Engagement Partnership Network, RIDE Council steering committee memberAbstract The number of disease-modifying therapies (DMTs) approved for the treatment of multiple sclerosis (MS) has greatly increased in recent decades, leading to higher treatment complexity. DMTs can differ in mode and frequency of administration, benefit–risk profile, and associated costs. Patients with MS contend not only with the burden of their chronic disease but also with the treatment burden of their MS therapy. Adhering to dosing schedules and infusion appointments can be difficult for busy, working-age patients or those with limited access to transportation. Patients and healthcare professionals (HCPs) may have differing priorities, concerns, and preferences when selecting treatment, potentially affecting treatment satisfaction and, importantly, adherence. Additionally, patients face direct and indirect costs related to treatment. These factors can all contribute to a high treatment burden on patients, impacting their quality of life and potentially leading to worse patient outcomes. HCPs, patients, and caregivers must work together to alleviate treatment burden through effective communication, shared decision-making, appreciating each other’s perspectives, and additional HCP support. Consideration of treatment burden into clinical guidelines is also warranted. In this review, we examine key factors impacting treatment burden for patients with MS, with a focus on the patient perspective as provided by our patient authors, and provide strategies to minimize treatment burden.https://doi.org/10.1007/s40120-024-00654-1Multiple sclerosisPatient perspectiveTreatment burden |
| spellingShingle | Barry A. Singer Dawn Morgan Julie A. Stamm Anita A. Williams Patient and Physician Perspectives of Treatment Burden in Multiple Sclerosis Neurology and Therapy Multiple sclerosis Patient perspective Treatment burden |
| title | Patient and Physician Perspectives of Treatment Burden in Multiple Sclerosis |
| title_full | Patient and Physician Perspectives of Treatment Burden in Multiple Sclerosis |
| title_fullStr | Patient and Physician Perspectives of Treatment Burden in Multiple Sclerosis |
| title_full_unstemmed | Patient and Physician Perspectives of Treatment Burden in Multiple Sclerosis |
| title_short | Patient and Physician Perspectives of Treatment Burden in Multiple Sclerosis |
| title_sort | patient and physician perspectives of treatment burden in multiple sclerosis |
| topic | Multiple sclerosis Patient perspective Treatment burden |
| url | https://doi.org/10.1007/s40120-024-00654-1 |
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