The Current Status in Terms of Vaccination for Individuals Infected with Human Immunodeficiency Virus
Human immunodeficiency virus (HIV)-infected individuals have an increased risk of various infections due to their impaired host immune system, resulting in higher morbidity and mortality rates. These patients severely suffered during the COVID-19 epidemic, the influenza epidemic and the spread of mo...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-01-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/17/2/171 |
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| author | Nan Xu Yanru Shen Weijin Huang Jianhui Nie |
| author_facet | Nan Xu Yanru Shen Weijin Huang Jianhui Nie |
| author_sort | Nan Xu |
| collection | DOAJ |
| description | Human immunodeficiency virus (HIV)-infected individuals have an increased risk of various infections due to their impaired host immune system, resulting in higher morbidity and mortality rates. These patients severely suffered during the COVID-19 epidemic, the influenza epidemic and the spread of monkeypox. Reducing serious infections is one of the most important measures to improve HIV-infected individuals’ quality and length of life. Based on the preparation processes and their antigenic properties, vaccines are divided into several types, including inactivated vaccines, attenuated live vaccines, recombinant protein vaccines, toxoid vaccines, polysaccharide vaccines, polysaccharide (protein) combined vaccines, nucleic acid vaccines, viral vector vaccines, etc. With the innovation of vaccine preparation technology in recent years and the acceleration of vaccine approval and market launch, more and more vaccine products suitable for HIV-infected individuals have become available. Because of their deficient immune systems, the type of vaccines and the schedule of vaccinations available to individuals living with HIV are sometimes different from those with healthy immune systems. This article reviewed the current status of vaccination in and shed light on the vaccination strategies for HIV-infected persons in terms of their safety and effectiveness. |
| format | Article |
| id | doaj-art-91c1f6208adf41cb9df83ec6f5dd0e9c |
| institution | OA Journals |
| issn | 1999-4915 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj-art-91c1f6208adf41cb9df83ec6f5dd0e9c2025-08-20T02:04:05ZengMDPI AGViruses1999-49152025-01-0117217110.3390/v17020171The Current Status in Terms of Vaccination for Individuals Infected with Human Immunodeficiency VirusNan Xu0Yanru Shen1Weijin Huang2Jianhui Nie3Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, National Institute for Food and Drug Control (NIFDC), State Key Laboratory of Drug Regulatory Science, Beijing 102629, ChinaDivision of HIV/AIDS and Sex-Transmitted Virus Vaccines, National Institute for Food and Drug Control (NIFDC), State Key Laboratory of Drug Regulatory Science, Beijing 102629, ChinaDivision of HIV/AIDS and Sex-Transmitted Virus Vaccines, National Institute for Food and Drug Control (NIFDC), State Key Laboratory of Drug Regulatory Science, Beijing 102629, ChinaDivision of HIV/AIDS and Sex-Transmitted Virus Vaccines, National Institute for Food and Drug Control (NIFDC), State Key Laboratory of Drug Regulatory Science, Beijing 102629, ChinaHuman immunodeficiency virus (HIV)-infected individuals have an increased risk of various infections due to their impaired host immune system, resulting in higher morbidity and mortality rates. These patients severely suffered during the COVID-19 epidemic, the influenza epidemic and the spread of monkeypox. Reducing serious infections is one of the most important measures to improve HIV-infected individuals’ quality and length of life. Based on the preparation processes and their antigenic properties, vaccines are divided into several types, including inactivated vaccines, attenuated live vaccines, recombinant protein vaccines, toxoid vaccines, polysaccharide vaccines, polysaccharide (protein) combined vaccines, nucleic acid vaccines, viral vector vaccines, etc. With the innovation of vaccine preparation technology in recent years and the acceleration of vaccine approval and market launch, more and more vaccine products suitable for HIV-infected individuals have become available. Because of their deficient immune systems, the type of vaccines and the schedule of vaccinations available to individuals living with HIV are sometimes different from those with healthy immune systems. This article reviewed the current status of vaccination in and shed light on the vaccination strategies for HIV-infected persons in terms of their safety and effectiveness.https://www.mdpi.com/1999-4915/17/2/171HIVHIV-infected individualvaccinationsafetyeffectiveness |
| spellingShingle | Nan Xu Yanru Shen Weijin Huang Jianhui Nie The Current Status in Terms of Vaccination for Individuals Infected with Human Immunodeficiency Virus Viruses HIV HIV-infected individual vaccination safety effectiveness |
| title | The Current Status in Terms of Vaccination for Individuals Infected with Human Immunodeficiency Virus |
| title_full | The Current Status in Terms of Vaccination for Individuals Infected with Human Immunodeficiency Virus |
| title_fullStr | The Current Status in Terms of Vaccination for Individuals Infected with Human Immunodeficiency Virus |
| title_full_unstemmed | The Current Status in Terms of Vaccination for Individuals Infected with Human Immunodeficiency Virus |
| title_short | The Current Status in Terms of Vaccination for Individuals Infected with Human Immunodeficiency Virus |
| title_sort | current status in terms of vaccination for individuals infected with human immunodeficiency virus |
| topic | HIV HIV-infected individual vaccination safety effectiveness |
| url | https://www.mdpi.com/1999-4915/17/2/171 |
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