Management of Wernicke's encephalopathy in a pregnant woman at 27 weeks gestation complicated by pre-eclampsia: A case report
Wernicke's Encephalopathy (WE) is a rare but severe condition primarily caused by thiamine deficiency, often seen in pregnant women who experience severe vomiting, such as in hyperemesis gravidarum. This case report details a 38-year-old woman at 27 weeks of gestation who developed altered cons...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-03-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043324013827 |
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| author | Amine Bensaid Marouane Boukroute Safae Bekkaoui Hajar Berrichi Abdelilah Elrhalete Hamza Mimouni Younes Oujidi Houssam Bkiyar Brahim Housni Ahmed Mimouni |
| author_facet | Amine Bensaid Marouane Boukroute Safae Bekkaoui Hajar Berrichi Abdelilah Elrhalete Hamza Mimouni Younes Oujidi Houssam Bkiyar Brahim Housni Ahmed Mimouni |
| author_sort | Amine Bensaid |
| collection | DOAJ |
| description | Wernicke's Encephalopathy (WE) is a rare but severe condition primarily caused by thiamine deficiency, often seen in pregnant women who experience severe vomiting, such as in hyperemesis gravidarum. This case report details a 38-year-old woman at 27 weeks of gestation who developed altered consciousness, cerebellar ataxia, and hyperlactatemia following persistent vomiting. Brain MRI demonstrated characteristic bilateral abnormalities consistent with WE. Early recognition and prompt intravenous thiamine administration led to significant clinical improvement. This case emphasizes the importance of maintaining a high level of suspicion and initiating immediate treatment to prevent irreversible neurological damage in pregnant women presenting with severe vomiting and neurological symptoms. A unique feature of this case is the development of Wernicke's encephalopathy secondary to hyperemesis gravidarum, further complicated by severe pre-eclampsia. |
| format | Article |
| id | doaj-art-91bd33690a7d413180b80a8156d296a3 |
| institution | Kabale University |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-91bd33690a7d413180b80a8156d296a32025-01-18T05:04:08ZengElsevierRadiology Case Reports1930-04332025-03-0120316581661Management of Wernicke's encephalopathy in a pregnant woman at 27 weeks gestation complicated by pre-eclampsia: A case reportAmine Bensaid0Marouane Boukroute1Safae Bekkaoui2Hajar Berrichi3Abdelilah Elrhalete4Hamza Mimouni5Younes Oujidi6Houssam Bkiyar7Brahim Housni8Ahmed Mimouni9Intensive Care Unit, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, Oujda, Morocco; Mohammed First University Oujda, Oujda, MoroccoDepartment of Obstetrics and Gynecology, Mohammed VI University Hospital Center, Faculty of Medecine and Pharmacy, Oujda, Morocco; Corresponding author.Intensive Care Unit, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, Oujda, MoroccoIntensive Care Unit, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, Oujda, MoroccoIntensive Care Unit, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, Oujda, MoroccoIntensive Care Unit, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, Oujda, Morocco; Mohammed First University Oujda, Oujda, MoroccoIntensive Care Unit, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, Oujda, Morocco; Mohammed First University Oujda, Oujda, MoroccoIntensive Care Unit, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, Oujda, Morocco; Mohammed First University Oujda, Oujda, MoroccoIntensive Care Unit, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, Oujda, Morocco; Mohammed First University Oujda, Oujda, MoroccoDepartment of Obstetrics and Gynecology, Mohammed VI University Hospital Center, Faculty of Medecine and Pharmacy, Oujda, Morocco; Mohammed First University Oujda, Oujda, MoroccoWernicke's Encephalopathy (WE) is a rare but severe condition primarily caused by thiamine deficiency, often seen in pregnant women who experience severe vomiting, such as in hyperemesis gravidarum. This case report details a 38-year-old woman at 27 weeks of gestation who developed altered consciousness, cerebellar ataxia, and hyperlactatemia following persistent vomiting. Brain MRI demonstrated characteristic bilateral abnormalities consistent with WE. Early recognition and prompt intravenous thiamine administration led to significant clinical improvement. This case emphasizes the importance of maintaining a high level of suspicion and initiating immediate treatment to prevent irreversible neurological damage in pregnant women presenting with severe vomiting and neurological symptoms. A unique feature of this case is the development of Wernicke's encephalopathy secondary to hyperemesis gravidarum, further complicated by severe pre-eclampsia.http://www.sciencedirect.com/science/article/pii/S1930043324013827Thiamine deficiencyWernicke's encephalopathyemergency MRIPre-eclampsia |
| spellingShingle | Amine Bensaid Marouane Boukroute Safae Bekkaoui Hajar Berrichi Abdelilah Elrhalete Hamza Mimouni Younes Oujidi Houssam Bkiyar Brahim Housni Ahmed Mimouni Management of Wernicke's encephalopathy in a pregnant woman at 27 weeks gestation complicated by pre-eclampsia: A case report Radiology Case Reports Thiamine deficiency Wernicke's encephalopathy emergency MRI Pre-eclampsia |
| title | Management of Wernicke's encephalopathy in a pregnant woman at 27 weeks gestation complicated by pre-eclampsia: A case report |
| title_full | Management of Wernicke's encephalopathy in a pregnant woman at 27 weeks gestation complicated by pre-eclampsia: A case report |
| title_fullStr | Management of Wernicke's encephalopathy in a pregnant woman at 27 weeks gestation complicated by pre-eclampsia: A case report |
| title_full_unstemmed | Management of Wernicke's encephalopathy in a pregnant woman at 27 weeks gestation complicated by pre-eclampsia: A case report |
| title_short | Management of Wernicke's encephalopathy in a pregnant woman at 27 weeks gestation complicated by pre-eclampsia: A case report |
| title_sort | management of wernicke s encephalopathy in a pregnant woman at 27 weeks gestation complicated by pre eclampsia a case report |
| topic | Thiamine deficiency Wernicke's encephalopathy emergency MRI Pre-eclampsia |
| url | http://www.sciencedirect.com/science/article/pii/S1930043324013827 |
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