Dissolving microneedle patch loaded with adipokines-enriched adipose extract relieves atopic dermatitis in mouse via modulating immune disorders, microbiota imbalance, and skin barrier defects

Dissolving microneedle patch loaded with adipokines-enriched adipose extract relieves atopic dermatitis in mouse via modulating immune disorders, microbiota imbalance, and skin barrier defects

Atopic dermatitis (AD) is a chronic relapsing dermatosis that demands new therapies. This research group previously developed a physically extracted adipose-derived extracellular matrix named adipose collagen fragments (ACF), which was determined containing massive adipose matrix-bound adipokines an...

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Bibliographic Details
Main Authors: Jingyan Guan, Kaiqi Chen, Feng Lu, Yunfan He
Format: Article
Language:English
Published: SAGE Publishing 2025-02-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314241312511
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