Effects of the fatty acid synthase inhibitors triclosan and lapatinib on dengue virus and Zika virus infection

Effects of the fatty acid synthase inhibitors triclosan and lapatinib on dengue virus and Zika virus infection

Abstract Fatty acid synthase (FASN) has been shown to be critical in the replication of several viruses of the genus Orthoflavivirus. In this study the role two inhibitors of FASN that work through different mechanisms were investigated in dengue virus (DENV) and Zika virus (ZIKV) infections. Triclo...

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Bibliographic Details
Main Authors: Suthatta Sornprasert, Janejira Jaratsittisin, Chanida Chumchanchira, Duncan R. Smith
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-95346-7
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