UFUR maintenance therapy significantly improves survival in locally advanced head and neck squamous cell carcinoma following definitive chemoradiotherapy

UFUR maintenance therapy significantly improves survival in locally advanced head and neck squamous cell carcinoma following definitive chemoradiotherapy

Abstract Background Head and neck squamous cell carcinoma (HNSCC) presents significant therapeutic challenges, particularly in patients with advanced disease. Despite advancements in treatment, high recurrence rates and poor overall survival (OS) remain major concerns. This study evaluates the impac...

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Main Authors: Jason Chia-Hsun Hsieh, Ming-Yu Lien, Pei-Hung Chang, Hung-Ming Wang, Kun-Yun Yeh, Ching-Liang Ho, Ching-Yun Hsieh, Meng-Che Hsieh, Jia-Hong Chen
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cancer Cell International
Subjects:
UFUR
HNSCC
Maintenance therapy
Recurrence-free survival
Overall survival
Online Access:https://doi.org/10.1186/s12935-025-03807-w
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