Study of acute toxicity, endothelial- and cardioprotective properties of phenolic and thiophenolic derivatives of 2H-imidazoles

Study of acute toxicity, endothelial- and cardioprotective properties of phenolic and thiophenolic derivatives of 2H-imidazoles

The aim. To study the acute toxicity, endothelial- and cardioprotective properties of phenolic and thiophenolic derivatives of 2H-imidazoles.Materials and methods. The study was performed on white laboratory female BALB/c mice (n=57) and male C57Bl/6 mice (n=66). Acute toxicity was assessed accordin...

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Main Authors: O. A. Puchenkova, O. V. Shheblykina, D. A. Kostina, A. A. Bolgov, P. R. Lebedev, V. V. Molchanov, T. G. Pokrovskaya, M. V. Korokin, E. A. Nikiforov, N. F. Vaskina, T. A. Idrisov, T. D. Moseev, V. V. Melekhin, M. V. Varaksin, V. N. Charushin, O. N. Chupakhin
Format: Article
Language:Russian
Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2025-07-01
Series:Фармация и фармакология (Пятигорск)
Subjects:
azaheterocyclic compounds
small molecules
endothelial dysfunction
imidazoles
phenols
thiophenols
Online Access:https://www.pharmpharm.ru/jour/article/view/1668
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