Disentangling the effects of sex and gender on APOE ɛ4–related neurocognitive impairment

Disentangling the effects of sex and gender on APOE ɛ4–related neurocognitive impairment

Abstract INTRODUCTION The apolipoprotein E (APOE) ɛ4 allele is a well‐established risk factor for neurocognitive impairment (NCI), with varying impacts between men and women. This study investigates the distinct roles of sex and gender in modifying APOE ɛ4–related NCI. METHODS Biological sex was inf...

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Main Authors: Tatiana Dessy, Amina Barhdadi, Marie‐Christyne Cyr, Johanna Sandoval, Louis Bherer, Joëlle Rouleau, Sylvie Provost, Louis‐Philippe Lemieux Perreault, Marie‐Pierre Sylvestre, Sarah A. Gagliano Taliun, Marie‐Pierre Dubé
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
apolipoprotein E
gender
neurocognitive impairment
sex difference
Online Access:https://doi.org/10.1002/dad2.70111
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