A secondary metabolite of Limosilactobacillus reuteri R2lc drives strain-specific pathology in a spontaneous mouse model of multiple sclerosis

A secondary metabolite of Limosilactobacillus reuteri R2lc drives strain-specific pathology in a spontaneous mouse model of multiple sclerosis

Summary: Limosilactobacillus reuteri is an immunomodulatory bacterium enriched in non-industrialized microbiomes, making it a therapeutic candidate for chronic diseases. However, effects of L. reuteri strains in mouse models of multiple sclerosis have been contradictory. Here, we show that treatment...

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Main Authors: Dale Archer, María Elisa Pérez-Muñoz, Stephanie Tollenaar, Simona Veniamin, Naomi Hotte, Christopher C. Cheng, Kristoff Nieves, Jee-Hwan Oh, Lilian Morceli, Susan Muncner, Daniel R. Barreda, Gurumoorthy Krishnamoorthy, Christopher Power, Jan-Peter van Pijkeren, Jens Walter
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Cell Reports
Subjects:
CP: Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725000920
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http://www.sciencedirect.com/science/article/pii/S2211124725000920

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