Synthesis, Physical Characterization and Biological Evaluation of Schiff BaseCr(III), Mn(III) and Fe(III) Complexes
M(III) complexes with Cr, Mn and Fe with Schiff base derived from 2-amino-4-ethyl-5-hydroxy benzaldehyde and oxocarbohydrazide were synthesized and characterized by several techniques using elemental analysis (C, H, N), molar conductance measurements, magnetic measurements, electronic, mass and IR s...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2010/623915 |
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| author | Gajendra Kumar Dharmendra Kumar Shoma Devi Amit Kumar Rajeev Johari |
| author_facet | Gajendra Kumar Dharmendra Kumar Shoma Devi Amit Kumar Rajeev Johari |
| author_sort | Gajendra Kumar |
| collection | DOAJ |
| description | M(III) complexes with Cr, Mn and Fe with Schiff base derived from 2-amino-4-ethyl-5-hydroxy benzaldehyde and oxocarbohydrazide were synthesized and characterized by several techniques using elemental analysis (C, H, N), molar conductance measurements, magnetic measurements, electronic, mass and IR spectral studies. On the bases of these studies, a five coordinated square pyramidal geometry for all these complexes has been proposed and found to be potential antimicrobial agent. The Schiff base ligand and complexes were also tested for their antimicrobial activity (against the bacteria Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Bacillus megaterium and the fungi Kluyveromyces fragilis, Rhodotorula rubra, Candida albicans and Trichoderma reesei) to assess their inhibiting potential. An attempt is also made to correlate the antimicrobial activity with geometry of the complexes. All complexes were found to be less active against the pathogens E.coli, S.aureus and P.aeruginosa. Cr(III) complex showed the best antimicrobial activity, but ligand alone was found to be active against the fungus T.reesei. |
| format | Article |
| id | doaj-art-918ab30c6c0c424d922fc7e6e96a047d |
| institution | DOAJ |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-918ab30c6c0c424d922fc7e6e96a047d2025-08-20T03:20:36ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017381382010.1155/2010/623915Synthesis, Physical Characterization and Biological Evaluation of Schiff BaseCr(III), Mn(III) and Fe(III) ComplexesGajendra Kumar0Dharmendra Kumar1Shoma Devi2Amit Kumar3Rajeev Johari4Department of Chemistry, Meerut College, Meerut, (U.P)-250001, IndiaDepartment of Chemistry, Vardhaman College, Bijnor (UP)-246701, IndiaDepartment of Life Science, Vardhaman College, Bijnor (UP)-246701, IndiaDepartment of Chemistry, Meerut College, Meerut, (U.P)-250001, IndiaDepartment of Chemistry, Vardhaman College, Bijnor (UP)-246701, IndiaM(III) complexes with Cr, Mn and Fe with Schiff base derived from 2-amino-4-ethyl-5-hydroxy benzaldehyde and oxocarbohydrazide were synthesized and characterized by several techniques using elemental analysis (C, H, N), molar conductance measurements, magnetic measurements, electronic, mass and IR spectral studies. On the bases of these studies, a five coordinated square pyramidal geometry for all these complexes has been proposed and found to be potential antimicrobial agent. The Schiff base ligand and complexes were also tested for their antimicrobial activity (against the bacteria Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Bacillus megaterium and the fungi Kluyveromyces fragilis, Rhodotorula rubra, Candida albicans and Trichoderma reesei) to assess their inhibiting potential. An attempt is also made to correlate the antimicrobial activity with geometry of the complexes. All complexes were found to be less active against the pathogens E.coli, S.aureus and P.aeruginosa. Cr(III) complex showed the best antimicrobial activity, but ligand alone was found to be active against the fungus T.reesei.http://dx.doi.org/10.1155/2010/623915 |
| spellingShingle | Gajendra Kumar Dharmendra Kumar Shoma Devi Amit Kumar Rajeev Johari Synthesis, Physical Characterization and Biological Evaluation of Schiff BaseCr(III), Mn(III) and Fe(III) Complexes E-Journal of Chemistry |
| title | Synthesis, Physical Characterization and Biological Evaluation of Schiff BaseCr(III), Mn(III) and Fe(III) Complexes |
| title_full | Synthesis, Physical Characterization and Biological Evaluation of Schiff BaseCr(III), Mn(III) and Fe(III) Complexes |
| title_fullStr | Synthesis, Physical Characterization and Biological Evaluation of Schiff BaseCr(III), Mn(III) and Fe(III) Complexes |
| title_full_unstemmed | Synthesis, Physical Characterization and Biological Evaluation of Schiff BaseCr(III), Mn(III) and Fe(III) Complexes |
| title_short | Synthesis, Physical Characterization and Biological Evaluation of Schiff BaseCr(III), Mn(III) and Fe(III) Complexes |
| title_sort | synthesis physical characterization and biological evaluation of schiff basecr iii mn iii and fe iii complexes |
| url | http://dx.doi.org/10.1155/2010/623915 |
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