The Child as a Surrogate for Diagnosis of Lupus in the Mother
Introduction. Neonatal lupus erythematosus (NLE) is an acquired disease of the newborn caused by transplacental transfer of maternal anti-Ro/SSA, anti-La/SSB, and infrequently anti-U1 RNP antibodies. Methodology. This is a case report of a male infant delivered via Caesarean section at 36-week gesta...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2017/8247591 |
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| author | Olufemi O. Adelowo Kenneth A. Ohagwu Ejiehi E. Aigbokhan Richard O. Akintayo |
| author_facet | Olufemi O. Adelowo Kenneth A. Ohagwu Ejiehi E. Aigbokhan Richard O. Akintayo |
| author_sort | Olufemi O. Adelowo |
| collection | DOAJ |
| description | Introduction. Neonatal lupus erythematosus (NLE) is an acquired disease of the newborn caused by transplacental transfer of maternal anti-Ro/SSA, anti-La/SSB, and infrequently anti-U1 RNP antibodies. Methodology. This is a case report of a male infant delivered via Caesarean section at 36-week gestation following detection of fetal bradycardia during routine antenatal clinic visit. Results. The mother was seropositive for antinuclear antibody (ANA) and anti-Ro/SSA and had elevated erythrocyte sedimentation rate. The baby was positive for ANA, extractable nuclear antigen (ENA), and anti-Ro/SSA. Pediatric echocardiography was abnormal and electrocardiography confirmed complete heart block. |
| format | Article |
| id | doaj-art-9186045d620e42d0b975d2bb2a328ccf |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-9186045d620e42d0b975d2bb2a328ccf2025-02-03T06:01:13ZengWileyCase Reports in Rheumatology2090-68892090-68972017-01-01201710.1155/2017/82475918247591The Child as a Surrogate for Diagnosis of Lupus in the MotherOlufemi O. Adelowo0Kenneth A. Ohagwu1Ejiehi E. Aigbokhan2Richard O. Akintayo3Rheumatology Unit, Department of Internal Medicine, Lagos State University Teaching Hospital, Ikeja, NigeriaRheumatology Unit, Internal Medicine Department, Federal Medical Centre, Umuahia, NigeriaRheumatology Unit, Department of Internal Medicine, University of Benin Teaching Hospital, Benin City, NigeriaRheumatology Unit, Department of Internal Medicine, University of Ilorin Teaching Hospital, Ilorin, NigeriaIntroduction. Neonatal lupus erythematosus (NLE) is an acquired disease of the newborn caused by transplacental transfer of maternal anti-Ro/SSA, anti-La/SSB, and infrequently anti-U1 RNP antibodies. Methodology. This is a case report of a male infant delivered via Caesarean section at 36-week gestation following detection of fetal bradycardia during routine antenatal clinic visit. Results. The mother was seropositive for antinuclear antibody (ANA) and anti-Ro/SSA and had elevated erythrocyte sedimentation rate. The baby was positive for ANA, extractable nuclear antigen (ENA), and anti-Ro/SSA. Pediatric echocardiography was abnormal and electrocardiography confirmed complete heart block.http://dx.doi.org/10.1155/2017/8247591 |
| spellingShingle | Olufemi O. Adelowo Kenneth A. Ohagwu Ejiehi E. Aigbokhan Richard O. Akintayo The Child as a Surrogate for Diagnosis of Lupus in the Mother Case Reports in Rheumatology |
| title | The Child as a Surrogate for Diagnosis of Lupus in the Mother |
| title_full | The Child as a Surrogate for Diagnosis of Lupus in the Mother |
| title_fullStr | The Child as a Surrogate for Diagnosis of Lupus in the Mother |
| title_full_unstemmed | The Child as a Surrogate for Diagnosis of Lupus in the Mother |
| title_short | The Child as a Surrogate for Diagnosis of Lupus in the Mother |
| title_sort | child as a surrogate for diagnosis of lupus in the mother |
| url | http://dx.doi.org/10.1155/2017/8247591 |
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