Multimodal Imaging and Macular Hyalocyte Count in a Patient with Acute Macular Neuroretinopathy
Though rare, acute macular neuroretinopathy is a well-described clinical entity. We report for the first time a detailed analysis of macular hyalocyte count and morphology during the acute phase of acute macular neuroretinopathy. We present a case of a 19-year-old man with bilateral acute onset para...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2022/2855191 |
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| author | Michael J. Schatz Oscar Otero-Marquez Richard B. Rosen Deep Parikh |
| author_facet | Michael J. Schatz Oscar Otero-Marquez Richard B. Rosen Deep Parikh |
| author_sort | Michael J. Schatz |
| collection | DOAJ |
| description | Though rare, acute macular neuroretinopathy is a well-described clinical entity. We report for the first time a detailed analysis of macular hyalocyte count and morphology during the acute phase of acute macular neuroretinopathy. We present a case of a 19-year-old man with bilateral acute onset paracentral scotomas in the setting of an antecedent viral infection. Multimodal imaging demonstrated classic features of acute macular neuroretinopathy. Further analysis revealed increased macular hyalocyte count and an activated hyalocyte morphology during the acute phase of the disease course. Multimodal imaging not only allows for greater confidence in a diagnosis and prognosis but also helps to shed light on underlying pathophysiology. The new clinical capability of monitoring cellular behavior, such as hyalocyte count and morphology, in physiological and pathological conditions may prove useful as biomarkers of early disease activity or response to therapy. |
| format | Article |
| id | doaj-art-9183f34e59b9410c804e6ca30901892e |
| institution | DOAJ |
| issn | 2090-6730 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-9183f34e59b9410c804e6ca30901892e2025-08-20T03:20:36ZengWileyCase Reports in Ophthalmological Medicine2090-67302022-01-01202210.1155/2022/2855191Multimodal Imaging and Macular Hyalocyte Count in a Patient with Acute Macular NeuroretinopathyMichael J. Schatz0Oscar Otero-Marquez1Richard B. Rosen2Deep Parikh3The New York Eye and Ear InfirmaryThe New York Eye and Ear InfirmaryThe New York Eye and Ear InfirmaryThe New York Eye and Ear InfirmaryThough rare, acute macular neuroretinopathy is a well-described clinical entity. We report for the first time a detailed analysis of macular hyalocyte count and morphology during the acute phase of acute macular neuroretinopathy. We present a case of a 19-year-old man with bilateral acute onset paracentral scotomas in the setting of an antecedent viral infection. Multimodal imaging demonstrated classic features of acute macular neuroretinopathy. Further analysis revealed increased macular hyalocyte count and an activated hyalocyte morphology during the acute phase of the disease course. Multimodal imaging not only allows for greater confidence in a diagnosis and prognosis but also helps to shed light on underlying pathophysiology. The new clinical capability of monitoring cellular behavior, such as hyalocyte count and morphology, in physiological and pathological conditions may prove useful as biomarkers of early disease activity or response to therapy.http://dx.doi.org/10.1155/2022/2855191 |
| spellingShingle | Michael J. Schatz Oscar Otero-Marquez Richard B. Rosen Deep Parikh Multimodal Imaging and Macular Hyalocyte Count in a Patient with Acute Macular Neuroretinopathy Case Reports in Ophthalmological Medicine |
| title | Multimodal Imaging and Macular Hyalocyte Count in a Patient with Acute Macular Neuroretinopathy |
| title_full | Multimodal Imaging and Macular Hyalocyte Count in a Patient with Acute Macular Neuroretinopathy |
| title_fullStr | Multimodal Imaging and Macular Hyalocyte Count in a Patient with Acute Macular Neuroretinopathy |
| title_full_unstemmed | Multimodal Imaging and Macular Hyalocyte Count in a Patient with Acute Macular Neuroretinopathy |
| title_short | Multimodal Imaging and Macular Hyalocyte Count in a Patient with Acute Macular Neuroretinopathy |
| title_sort | multimodal imaging and macular hyalocyte count in a patient with acute macular neuroretinopathy |
| url | http://dx.doi.org/10.1155/2022/2855191 |
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