From Ethnopharmacology to Active Compound: Effects of Traditional Plant Extracts on Varicose Vein-Related Enzymes and Isolation of Active Flavonoids from <i>Helichrysum plicatum</i> DC. subsp. <i>plicatum</i>

From Ethnopharmacology to Active Compound: Effects of Traditional Plant Extracts on Varicose Vein-Related Enzymes and Isolation of Active Flavonoids from <i>Helichrysum plicatum</i> DC. subsp. <i>plicatum</i>

<b>Background:</b> Varicose veins and chronic venous insufficiency are chronic venous disorders involving abnormalities in the venous system. Inflammation, an increase in proteolytic enzymes, and free radicals are important factors that play a role in the varicose vein pathology. <b&g...

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Bibliographic Details
Main Authors: Tugsen Buyukyildirim, F. Sezer Senol Deniz, Merve Yuzbasioglu Baran, Ece Salihoglu, Mustafa Abdullah Yilmaz, Osman Tugay
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceuticals
Subjects:
<i>Helichrysum plicatum</i> subsp. <i>plicatum</i>
varicose vein
in vitro enzyme inhibition activity
antioxidant activity
flavonoids
naringenin
Online Access:https://www.mdpi.com/1424-8247/18/6/926
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