A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment
Primary central nervous system lymphomas (PCNSLs) are mainly B-cells lymphomas. A risk factor for the development of PCNSL is immunodeficiency, which includes congenital disorders, iatrogenic immunosuppression, and HIV. The clinical course is rapidly fatal; these patients usually present signs of in...
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2013-01-01
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Series: | Case Reports in Radiology |
Online Access: | http://dx.doi.org/10.1155/2013/916348 |
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author | G. Manenti F. Di Giuliano A. Bindi V. Liberto V. Funel F. G. Garaci R. Floris G. Simonetti |
author_facet | G. Manenti F. Di Giuliano A. Bindi V. Liberto V. Funel F. G. Garaci R. Floris G. Simonetti |
author_sort | G. Manenti |
collection | DOAJ |
description | Primary central nervous system lymphomas (PCNSLs) are mainly B-cells lymphomas. A risk factor for the development of PCNSL is immunodeficiency, which includes congenital disorders, iatrogenic immunosuppression, and HIV. The clinical course is rapidly fatal; these patients usually present signs of increased intracranial pressure, nausea, papilledema, vomiting, and neurological and neuropsychiatric symptoms. PCNSL may have a characteristic appearance on CT and MR imaging. DWI sequences and MR spectroscopy may help to differentiate CNS lymphomas from other brain lesions. In this paper, we report a case of a 23-year-old man with T-primary central nervous system lymphoma presenting with a mass in the right frontotemporal lobe. We describe clinical, CT, and MRI findings. Diagnosis was confirmed by stereotactic biopsy of the lesion. |
format | Article |
id | doaj-art-917d05d725f3486f8098aba3cc72dd93 |
institution | Kabale University |
issn | 2090-6862 2090-6870 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Radiology |
spelling | doaj-art-917d05d725f3486f8098aba3cc72dd932025-02-03T05:47:16ZengWileyCase Reports in Radiology2090-68622090-68702013-01-01201310.1155/2013/916348916348A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy AssessmentG. Manenti0F. Di Giuliano1A. Bindi2V. Liberto3V. Funel4F. G. Garaci5R. Floris6G. Simonetti7Department of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyPrimary central nervous system lymphomas (PCNSLs) are mainly B-cells lymphomas. A risk factor for the development of PCNSL is immunodeficiency, which includes congenital disorders, iatrogenic immunosuppression, and HIV. The clinical course is rapidly fatal; these patients usually present signs of increased intracranial pressure, nausea, papilledema, vomiting, and neurological and neuropsychiatric symptoms. PCNSL may have a characteristic appearance on CT and MR imaging. DWI sequences and MR spectroscopy may help to differentiate CNS lymphomas from other brain lesions. In this paper, we report a case of a 23-year-old man with T-primary central nervous system lymphoma presenting with a mass in the right frontotemporal lobe. We describe clinical, CT, and MRI findings. Diagnosis was confirmed by stereotactic biopsy of the lesion.http://dx.doi.org/10.1155/2013/916348 |
spellingShingle | G. Manenti F. Di Giuliano A. Bindi V. Liberto V. Funel F. G. Garaci R. Floris G. Simonetti A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment Case Reports in Radiology |
title | A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment |
title_full | A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment |
title_fullStr | A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment |
title_full_unstemmed | A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment |
title_short | A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment |
title_sort | case of primary t cell central nervous system lymphoma mr imaging and mr spectroscopy assessment |
url | http://dx.doi.org/10.1155/2013/916348 |
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