A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment

Primary central nervous system lymphomas (PCNSLs) are mainly B-cells lymphomas. A risk factor for the development of PCNSL is immunodeficiency, which includes congenital disorders, iatrogenic immunosuppression, and HIV. The clinical course is rapidly fatal; these patients usually present signs of in...

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Main Authors: G. Manenti, F. Di Giuliano, A. Bindi, V. Liberto, V. Funel, F. G. Garaci, R. Floris, G. Simonetti
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2013/916348
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author G. Manenti
F. Di Giuliano
A. Bindi
V. Liberto
V. Funel
F. G. Garaci
R. Floris
G. Simonetti
author_facet G. Manenti
F. Di Giuliano
A. Bindi
V. Liberto
V. Funel
F. G. Garaci
R. Floris
G. Simonetti
author_sort G. Manenti
collection DOAJ
description Primary central nervous system lymphomas (PCNSLs) are mainly B-cells lymphomas. A risk factor for the development of PCNSL is immunodeficiency, which includes congenital disorders, iatrogenic immunosuppression, and HIV. The clinical course is rapidly fatal; these patients usually present signs of increased intracranial pressure, nausea, papilledema, vomiting, and neurological and neuropsychiatric symptoms. PCNSL may have a characteristic appearance on CT and MR imaging. DWI sequences and MR spectroscopy may help to differentiate CNS lymphomas from other brain lesions. In this paper, we report a case of a 23-year-old man with T-primary central nervous system lymphoma presenting with a mass in the right frontotemporal lobe. We describe clinical, CT, and MRI findings. Diagnosis was confirmed by stereotactic biopsy of the lesion.
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institution Kabale University
issn 2090-6862
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publishDate 2013-01-01
publisher Wiley
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series Case Reports in Radiology
spelling doaj-art-917d05d725f3486f8098aba3cc72dd932025-02-03T05:47:16ZengWileyCase Reports in Radiology2090-68622090-68702013-01-01201310.1155/2013/916348916348A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy AssessmentG. Manenti0F. Di Giuliano1A. Bindi2V. Liberto3V. Funel4F. G. Garaci5R. Floris6G. Simonetti7Department of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyDepartment of Diagnostic and Interventional Radiology, Molecular Imaging and Radiation Therapy, Policlinico Tor Vergata, Viale Oxford 81, 00133 Rome, ItalyPrimary central nervous system lymphomas (PCNSLs) are mainly B-cells lymphomas. A risk factor for the development of PCNSL is immunodeficiency, which includes congenital disorders, iatrogenic immunosuppression, and HIV. The clinical course is rapidly fatal; these patients usually present signs of increased intracranial pressure, nausea, papilledema, vomiting, and neurological and neuropsychiatric symptoms. PCNSL may have a characteristic appearance on CT and MR imaging. DWI sequences and MR spectroscopy may help to differentiate CNS lymphomas from other brain lesions. In this paper, we report a case of a 23-year-old man with T-primary central nervous system lymphoma presenting with a mass in the right frontotemporal lobe. We describe clinical, CT, and MRI findings. Diagnosis was confirmed by stereotactic biopsy of the lesion.http://dx.doi.org/10.1155/2013/916348
spellingShingle G. Manenti
F. Di Giuliano
A. Bindi
V. Liberto
V. Funel
F. G. Garaci
R. Floris
G. Simonetti
A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment
Case Reports in Radiology
title A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment
title_full A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment
title_fullStr A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment
title_full_unstemmed A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment
title_short A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment
title_sort case of primary t cell central nervous system lymphoma mr imaging and mr spectroscopy assessment
url http://dx.doi.org/10.1155/2013/916348
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