Genes adopt non‐optimal codon usage to generate cell cycle‐dependent oscillations in protein levels

Abstract The cell cycle is a temporal program that regulates DNA synthesis and cell division. When we compared the codon usage of cell cycle‐regulated genes with that of other genes, we discovered that there is a significant preference for non‐optimal codons. Moreover, genes encoding proteins that c...

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Bibliographic Details
Main Authors: Milana Frenkel‐Morgenstern, Tamar Danon, Thomas Christian, Takao Igarashi, Lydia Cohen, Ya‐Ming Hou, Lars Juhl Jensen
Format: Article
Language:English
Published: Springer Nature 2012-02-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.1038/msb.2012.3
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