Genes adopt non‐optimal codon usage to generate cell cycle‐dependent oscillations in protein levels
Abstract The cell cycle is a temporal program that regulates DNA synthesis and cell division. When we compared the codon usage of cell cycle‐regulated genes with that of other genes, we discovered that there is a significant preference for non‐optimal codons. Moreover, genes encoding proteins that c...
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| Main Authors: | Milana Frenkel‐Morgenstern, Tamar Danon, Thomas Christian, Takao Igarashi, Lydia Cohen, Ya‐Ming Hou, Lars Juhl Jensen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2012-02-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/msb.2012.3 |
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