Insulin resistance as a mediator of the association between obesity, high-intensity binge drinking, and liver enzyme abnormalities in young and middle-aged adults: a cross-sectional study

Insulin resistance as a mediator of the association between obesity, high-intensity binge drinking, and liver enzyme abnormalities in young and middle-aged adults: a cross-sectional study

BackgroundBinge drinking (BD) and obesity are well-established risk factors for liver enzyme abnormalities, but how varying intensities of BD interact with obesity to affect liver function remains unclear. This study aims to examine whether insulin resistance (IR) mediates the associations between d...

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Main Authors: Jiayi Zhu, Yinglong Duan, Ying Li, Yi Zhou, Zitong Lu, Nandan Chen, Juan Luo, Xingxing Wang, Xiaoqian Dong, Andy S. K. Cheng, Yuan Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Nutrition
Subjects:
insulin resistance
obesity
binge drinking
liver enzymes
metabolic dysfunction
young and middle-aged
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1554392/full
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