Revised safety evaluation of the food enzyme glucose oxidase from the genetically modified Trichoderma reesei strain AR‐352
Abstract The food enzyme glucose oxidase (β‐d‐glucose: oxygen 1‐oxidoreductase; EC 1.1.3.4) is produced with the genetically modified Trichoderma reesei strain AR‐352 by AB Enzymes GmbH. In a previous opinion, the Panel on Food Contact Materials, Enzymes and Processing Aids of the European Food Safe...
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| Format: | Article |
| Language: | English |
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Wiley
2024-12-01
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| Series: | EFSA Journal |
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| Online Access: | https://doi.org/10.2903/j.efsa.2024.9122 |
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| author | EFSA Panel on Food Enzymes (FEZ) Holger Zorn José Manuel Barat Baviera Claudia Bolognesi Francesco Catania Gabriele Gadermaier Ralf Greiner Baltasar Mayo Alicja Mortensen Yrjö Henrik Roos Marize L. M. Solano Monika Sramkova Henk Van Loveren Laurence Vernis Jaime Aguilera Yi Liu |
| author_facet | EFSA Panel on Food Enzymes (FEZ) Holger Zorn José Manuel Barat Baviera Claudia Bolognesi Francesco Catania Gabriele Gadermaier Ralf Greiner Baltasar Mayo Alicja Mortensen Yrjö Henrik Roos Marize L. M. Solano Monika Sramkova Henk Van Loveren Laurence Vernis Jaime Aguilera Yi Liu |
| author_sort | EFSA Panel on Food Enzymes (FEZ) |
| collection | DOAJ |
| description | Abstract The food enzyme glucose oxidase (β‐d‐glucose: oxygen 1‐oxidoreductase; EC 1.1.3.4) is produced with the genetically modified Trichoderma reesei strain AR‐352 by AB Enzymes GmbH. In a previous opinion, the Panel on Food Contact Materials, Enzymes and Processing Aids of the European Food Safety Authority could not conclude on the absence of recombinant DNA from the production strain in the food enzyme due to uncertainties about the limit of detection of the applied methodology. New data provided by the applicant showed that no DNA from the production strain was found in the food enzyme with a limit of detection meeting the requirements of the applicable guidance. Based on the new data provided, the Panel concludes that this food enzyme is free from recombinant DNA from the production strain. |
| format | Article |
| id | doaj-art-9162730611bb4d57bc5dd9eef641769e |
| institution | Kabale University |
| issn | 1831-4732 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | EFSA Journal |
| spelling | doaj-art-9162730611bb4d57bc5dd9eef641769e2025-01-17T06:31:16ZengWileyEFSA Journal1831-47322024-12-012212n/an/a10.2903/j.efsa.2024.9122Revised safety evaluation of the food enzyme glucose oxidase from the genetically modified Trichoderma reesei strain AR‐352EFSA Panel on Food Enzymes (FEZ)Holger ZornJosé Manuel Barat BavieraClaudia BolognesiFrancesco CataniaGabriele GadermaierRalf GreinerBaltasar MayoAlicja MortensenYrjö Henrik RoosMarize L. M. SolanoMonika SramkovaHenk Van LoverenLaurence VernisJaime AguileraYi LiuAbstract The food enzyme glucose oxidase (β‐d‐glucose: oxygen 1‐oxidoreductase; EC 1.1.3.4) is produced with the genetically modified Trichoderma reesei strain AR‐352 by AB Enzymes GmbH. In a previous opinion, the Panel on Food Contact Materials, Enzymes and Processing Aids of the European Food Safety Authority could not conclude on the absence of recombinant DNA from the production strain in the food enzyme due to uncertainties about the limit of detection of the applied methodology. New data provided by the applicant showed that no DNA from the production strain was found in the food enzyme with a limit of detection meeting the requirements of the applicable guidance. Based on the new data provided, the Panel concludes that this food enzyme is free from recombinant DNA from the production strain.https://doi.org/10.2903/j.efsa.2024.9122EC 1.1.3.4EFSA‐Q‐2021‐00298EFSA‐Q‐2024‐00167food enzymegenetically modified microorganismglucose oxidase |
| spellingShingle | EFSA Panel on Food Enzymes (FEZ) Holger Zorn José Manuel Barat Baviera Claudia Bolognesi Francesco Catania Gabriele Gadermaier Ralf Greiner Baltasar Mayo Alicja Mortensen Yrjö Henrik Roos Marize L. M. Solano Monika Sramkova Henk Van Loveren Laurence Vernis Jaime Aguilera Yi Liu Revised safety evaluation of the food enzyme glucose oxidase from the genetically modified Trichoderma reesei strain AR‐352 EFSA Journal EC 1.1.3.4 EFSA‐Q‐2021‐00298 EFSA‐Q‐2024‐00167 food enzyme genetically modified microorganism glucose oxidase |
| title | Revised safety evaluation of the food enzyme glucose oxidase from the genetically modified Trichoderma reesei strain AR‐352 |
| title_full | Revised safety evaluation of the food enzyme glucose oxidase from the genetically modified Trichoderma reesei strain AR‐352 |
| title_fullStr | Revised safety evaluation of the food enzyme glucose oxidase from the genetically modified Trichoderma reesei strain AR‐352 |
| title_full_unstemmed | Revised safety evaluation of the food enzyme glucose oxidase from the genetically modified Trichoderma reesei strain AR‐352 |
| title_short | Revised safety evaluation of the food enzyme glucose oxidase from the genetically modified Trichoderma reesei strain AR‐352 |
| title_sort | revised safety evaluation of the food enzyme glucose oxidase from the genetically modified trichoderma reesei strain ar 352 |
| topic | EC 1.1.3.4 EFSA‐Q‐2021‐00298 EFSA‐Q‐2024‐00167 food enzyme genetically modified microorganism glucose oxidase |
| url | https://doi.org/10.2903/j.efsa.2024.9122 |
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