A Perspective Review on Numerical Simulations of Hemodynamics in Aortic Dissection
Aortic dissection, characterized by separation of the layers of the aortic wall, poses a significant challenge for clinicians. While type A aortic dissection patients are normally managed using surgical treatment, optimal treatment strategy for type B aortic dissection remains controversial and requ...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/652520 |
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| author | Wan Naimah Wan Ab Naim Poo Balan Ganesan Zhonghua Sun Kok Han Chee Shahrul Amry Hashim Einly Lim |
| author_facet | Wan Naimah Wan Ab Naim Poo Balan Ganesan Zhonghua Sun Kok Han Chee Shahrul Amry Hashim Einly Lim |
| author_sort | Wan Naimah Wan Ab Naim |
| collection | DOAJ |
| description | Aortic dissection, characterized by separation of the layers of the aortic wall, poses a significant challenge for clinicians. While type A aortic dissection patients are normally managed using surgical treatment, optimal treatment strategy for type B aortic dissection remains controversial and requires further evaluation. Although aortic diameter measured by CT angiography has been clinically used as a guideline to predict dilation in aortic dissection, hemodynamic parameters (e.g., pressure and wall shear stress), geometrical factors, and composition of the aorta wall are known to substantially affect disease progression. Due to the limitations of cardiac imaging modalities, numerical simulations have been widely used for the prediction of disease progression and therapeutic outcomes, by providing detailed insights into the hemodynamics. This paper presents a comprehensive review of the existing numerical models developed to investigate reasons behind tear initiation and progression, as well as the effectiveness of various treatment strategies, particularly the stent graft treatment. |
| format | Article |
| id | doaj-art-91625f44291a4c36bd65759892271f6a |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-91625f44291a4c36bd65759892271f6a2025-02-03T01:25:28ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/652520652520A Perspective Review on Numerical Simulations of Hemodynamics in Aortic DissectionWan Naimah Wan Ab Naim0Poo Balan Ganesan1Zhonghua Sun2Kok Han Chee3Shahrul Amry Hashim4Einly Lim5Department of Biomedical Engineering, Faculty of Engineering Building, University of Malaya, 50603 Kuala Lumpur, KL, MalaysiaDepartment of Mechanical Engineering, Faculty of Engineering Building, University of Malaya, 50603 Kuala Lumpur, KL, MalaysiaDiscipline of Medical Imaging, Department of Imaging and Applied Physics, Curtin University, Perth, WA 6845, AustraliaDepartment of Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, KL, MalaysiaDepartment of Surgery, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, KL, MalaysiaDepartment of Biomedical Engineering, Faculty of Engineering Building, University of Malaya, 50603 Kuala Lumpur, KL, MalaysiaAortic dissection, characterized by separation of the layers of the aortic wall, poses a significant challenge for clinicians. While type A aortic dissection patients are normally managed using surgical treatment, optimal treatment strategy for type B aortic dissection remains controversial and requires further evaluation. Although aortic diameter measured by CT angiography has been clinically used as a guideline to predict dilation in aortic dissection, hemodynamic parameters (e.g., pressure and wall shear stress), geometrical factors, and composition of the aorta wall are known to substantially affect disease progression. Due to the limitations of cardiac imaging modalities, numerical simulations have been widely used for the prediction of disease progression and therapeutic outcomes, by providing detailed insights into the hemodynamics. This paper presents a comprehensive review of the existing numerical models developed to investigate reasons behind tear initiation and progression, as well as the effectiveness of various treatment strategies, particularly the stent graft treatment.http://dx.doi.org/10.1155/2014/652520 |
| spellingShingle | Wan Naimah Wan Ab Naim Poo Balan Ganesan Zhonghua Sun Kok Han Chee Shahrul Amry Hashim Einly Lim A Perspective Review on Numerical Simulations of Hemodynamics in Aortic Dissection The Scientific World Journal |
| title | A Perspective Review on Numerical Simulations of Hemodynamics in Aortic Dissection |
| title_full | A Perspective Review on Numerical Simulations of Hemodynamics in Aortic Dissection |
| title_fullStr | A Perspective Review on Numerical Simulations of Hemodynamics in Aortic Dissection |
| title_full_unstemmed | A Perspective Review on Numerical Simulations of Hemodynamics in Aortic Dissection |
| title_short | A Perspective Review on Numerical Simulations of Hemodynamics in Aortic Dissection |
| title_sort | perspective review on numerical simulations of hemodynamics in aortic dissection |
| url | http://dx.doi.org/10.1155/2014/652520 |
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