Sex-specific modulation of anxiety-like behavior by forebrain neuronal SMC3 in mice

Abstract SMC3 is a chromatin binding factor that plays central roles in genome organization and in proper neurodevelopment. Mutations in SMC3 gene (SMC3) induce neurodevelopmental and behavioral phenotypes in humans, including changes in anxiety behavior and self-injury. However, it is not clear wha...

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Bibliographic Details
Main Authors: Natalia Saleev, Dmitriy Getselter, Evan Elliott
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03494-1
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