Oral Angiotensin-(1-7) formulation after established elastase-induced emphysema suppresses inflammation and restores lung architecture

BackgroundChronic obstructive pulmonary disease (COPD), a prevalent age-related condition, ranks among the leading causes of global mortality. It is characterized by chronic inflammation, cellular senescence, and irreversible lung tissue damage, with no curative treatments currently available. Angio...

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Bibliographic Details
Main Authors:	Giselle Santos Magalhaes, Alicia Villacampa, Maria Gloria Rodrigues-Machado, Maria Jose Campagnole-Santos, Robson Augusto Souza Santos, Carlos F. Sánchez-Ferrer, Concepción Peiró
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Pharmacology
Subjects:	chronic inflammation cellular senescence alveolar regeneration Wnt/β-catenin pathway NF-κB modulation
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1540475/full
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Oral Angiotensin-(1-7) formulation after established elastase-induced emphysema suppresses inflammation and restores lung architecture

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