Regulatory roles of an sRNA derived from the 5´ UTR and sequence internal to lapA in Pseudomonas aeruginosa PAO1

Regulatory roles of an sRNA derived from the 5´ UTR and sequence internal to lapA in Pseudomonas aeruginosa PAO1

ABSTRACT Several key virulence factors of Pseudomonas aeruginosa are regulated by quorum-sensing systems, small noncoding RNAs (sRNAs), and environmental stress, leading to a high mortality rate. Our previous studies indicated that the alkaline phosphatase LapA regulated P. aeruginosa PAO1 biofilm f...

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Main Authors: Xiaojuan Tan, Jingjing Xiao, Qianqian Liu, Ting Yang, Dandan Feng, Ruyi Zheng, Liping Luo, Xi Cheng, Dongsheng Du, Minghui Li, Jinwei Zhou, Guoping Zhu
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:Microbiology Spectrum
Subjects:
Pseudomonas aeruginosa
sRNA LapS
alkaline phosphatase LapA
virulence factors
biofilms
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01303-24
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